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ABCD1 Polyclonal Antibody

规格: / 20μL / 60μL / 120μL / 200μL
价格: / ¥420 / ¥1010 / ¥1640 / ¥2365

货号:E-AB-19528

宿主: Rabbit

反应性: H,M

应用: IHC

  • 详情
  • Overview

    Synonyms ABC42,Abcd1,ABCD1,Adrenoleukodystrophy protein,ALD,Aldgh,ALDP,AMN,ATP binding cassette,sub family D (ALD),member 1,ATP-binding cassette sub-family D member 1,OTTHUMP00000025960,OTTMUSP00000019283,RGD1562128,RP23 373N8.2,X linked adrenoleukodystrophy (ALD) gene homolog,ABCD1抗体
    Swissprot P33897
    Source Rabbit
    Reactivity Human, Mouse
    Immunogen Synthetic peptide of human ABCD1
    Application IHC(Detection kit: E-IR-R213)
    Recommended dilution IHC,,1:60-1:450;
    Concentration 1.5mg/mL
    Clonality Polyclonal

    Properties

    Cellular localization Peroxisome membrane.
    Isotype IgG
    Purification Affinity purification
    Conjugation Unconjugated
    Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
    Storage buffer PBS with 0.05% NaN3 and 40% Glycerol,pH7.4
    Background ABCD1 (also known as ALDP) is a member of the ATP-binding cassette (ABC) transporter superfamily which functions as transporter for a wide variety of substrates. It localizes to the peroxisomal membrane. The exact function is not clear so far. Various mutations of ABCD1 cause X-linked adrenoleukodystrophy (X-ALD),an inherited neurodegenerative disease affecting the nervous system white matter and adrenal cortex.
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