ABCD1 Polyclonal Antibody
规格: | / 20μL / 60μL / 120μL / 200μL |
价格: | / ¥420 / ¥1010 / ¥1640 / ¥2365 |
货号:E-AB-19528
宿主: Rabbit
反应性: H,M
应用: IHC
Overview
Synonyms | ABC42,Abcd1,ABCD1,Adrenoleukodystrophy protein,ALD,Aldgh,ALDP,AMN,ATP binding cassette,sub family D (ALD),member 1,ATP-binding cassette sub-family D member 1,OTTHUMP00000025960,OTTMUSP00000019283,RGD1562128,RP23 373N8.2,X linked adrenoleukodystrophy (ALD) gene homolog,ABCD1抗体 |
Swissprot | P33897 |
Source | Rabbit |
Reactivity | Human, Mouse |
Immunogen | Synthetic peptide of human ABCD1 |
Application | IHC(Detection kit: E-IR-R213) |
Recommended dilution | IHC,,1:60-1:450; |
Concentration | 1.5mg/mL |
Clonality | Polyclonal |
Properties
Cellular localization | Peroxisome membrane. |
Isotype | IgG |
Purification | Affinity purification |
Conjugation | Unconjugated |
Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
Storage buffer | PBS with 0.05% NaN3 and 40% Glycerol,pH7.4 |
Background | ABCD1 (also known as ALDP) is a member of the ATP-binding cassette (ABC) transporter superfamily which functions as transporter for a wide variety of substrates. It localizes to the peroxisomal membrane. The exact function is not clear so far. Various mutations of ABCD1 cause X-linked adrenoleukodystrophy (X-ALD),an inherited neurodegenerative disease affecting the nervous system white matter and adrenal cortex. |