ABI3BP Polyclonal Antibody
| 规格： | / 20μL / 60μL / 120μL / 200μL |
| 价格： | / ￥420 / ￥1010 / ￥1640 / ￥2365 |
货号：E-AB-10970
宿主: Rabbit
反应性: H
应用: IHC
Overview
| Synonyms | ABI gene family member 3 (NESH) binding protein,ABI gene family member 3 binding protein,ABI gene family member 3-binding protein,ABI3BP,FLJ41743,FLJ41754,Nesh binding protein,Nesh BP,Nesh-binding protein,NeshBP,Target of Nesh SH3,Target of Nesh-SH3,Tarsh,TARSH,ABI3BP抗体 |
| Swissprot | Q7Z7G0 |
| Source | Rabbit |
| Reactivity | Human |
| Immunogen | Recombinant protein of human ABI3BP |
| Application | IHC(Detection kit: E-IR-R213) |
| Recommended dilution | IHC,,1:50-1:200 |
| Concentration | 0.7 mg/mL |
| Clonality | Polyclonal |
Properties
| Cellular localization | Secreted. |
| Tissue specificity | Expressed in brain, heart, lung, liver, pancreas kidney and placenta. |
| Isotype | IgG |
| Purification | Affinity purification |
| Conjugation | Unconjugated |
| Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage buffer | PBS with 0.05% sodium azide, 50% glycerol, PH7.3 |
| Background | A target of NESH-SH3/Abi3bp (TARSH) was originally identified as an SH3 domain-binding molecule of the NESH-SH3/Abi3 protein that is involved in Rac-dependent actin polymerization. In recent studies, TARSH gene expression was dramatically induced in mouse embryonic fibroblasts (MEFs) replicative senescence and suppressed in human lung carcinoma specimens and thyroid carcinomas. However, the molecular mechanism underlying the regulation of TARSH in tumorigenesis remains unclear. |
