ACE1 Polyclonal Antibody
| 规格： | / 60μL / 120μL / 200μL |
| 价格： | / ￥1380 / ￥2220 / ￥3300 |
货号：E-AB-70116
宿主: Rabbit
反应性: R
应用: IHC
Overview
| Synonyms | ACE 1,ACE,ACE T,ACE,ACE1,Angiotensin converting enzyme somatic isoform,Angiotensin converting enzyme testis specific isoform,Angiotensin I converting enzyme 1,Angiotensin I converting enzyme,Angiotensin I converting enzyme peptidyl dipeptidase A 1,angiotensin I converting enzyme peptidyl-dipeptidase A 1 transcript,Angiotensin-converting enzyme,Carboxycathepsin,CD 143,CD143,CD143 antigen,DCP 1,DCP,DCP1,Dipeptidyl carboxypeptidase 1,Dipeptidyl carboxypeptidase I,Kininase II,MGC26566,MVCD3,Peptidase P,Peptidyl dipeptidase A,soluble form,Testicular ECA,ACE1抗体 |
| Swissprot | P09470,P47820 |
| Source | Rabbit |
| Reactivity | Rat |
| Immunogen | KLH conjugated Synthetic peptide corresponding to Mouse ACE |
| Application | IHC(Detection kit: E-IR-R213) |
| Recommended dilution | IHC,,1:300-1:1000 |
| Concentration | 200 μg/mL |
| Clonality | Polyclonal |
Properties
| Cellular localization | Secreted and Cell membrane. |
| Tissue specificity | Testis-specific isoform is expressed in spermatocytes, adult testis.Highest expression level in jejunum. |
| Isotype | IgG |
| Purification | Affinity purification |
| Conjugation | Unconjugated |
| Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage buffer | PBS with 0.02% sodium azide,100 μg/ml BSA and 50% glycerol. |
| Background | This gene encodes an enzyme involved in catalyzing the conversion of angiotensin I into a physiologically active peptide angiotensin II. Angiotensin II is a potent vasopressor and aldosterone-stimulating peptide that controls blood pressure and fluid-electrolyte balance. This enzyme plays a key role in the renin-angiotensin system. Many studies have associated the presence or absence of a 287 bp Alu repeat element in this gene with the levels of circulating enzyme or cardiovascular pathophysiologies. Multiple alternatively spliced transcript variants encoding different isoforms have been identified, and two most abundant spliced variants encode the somatic form and the testicular form, respectively, that are equally active. |
