ACIN1 Polyclonal Antibody
规格: | / 20μL / 60μL / 120μL / 200μL |
价格: | / ¥420 / ¥1010 / ¥1640 / ¥2365 |
货号:E-AB-16128
宿主: Rabbit
反应性: H,M
应用: IHC
Overview
Synonyms | ACIN 1,ACIN1,ACINU,Acinus,ACN,Apoptotic chromatin condensation inducer 1,Apoptotic chromatin condensation inducer in the nucleus,DKFZp667N107,fSAP152,functional spliceosome-associated protein 152,KIAA0670,ACIN1抗体 |
Swissprot | Q9UKV3 |
Source | Rabbit |
Reactivity | Human,Mouse |
Immunogen | Synthetic peptide of human ACIN1 |
Application | IHC(Detection kit: E-IR-R213) |
Recommended dilution | IHC,,1:100-1:300 |
Concentration | 0.6 mg/mL |
Clonality | Polyclonal |
Properties
Cellular localization | Nucleus. |
Tissue specificity | Ubiquitous. |
Isotype | IgG |
Purification | Affinity purification |
Conjugation | Unconjugated |
Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
Storage buffer | PBS with 0.05% sodium azide, 50% glycerol, PH7.3 |
Background | Apoptosis is defined by several morphologic nuclear changes, including chromatin condensation and nuclear fragmentation. This gene encodes a nuclear protein that induces apoptotic chromatin condensation after activation by caspase-3, without inducing DNA fragmentation. This protein has also been shown to be a component of a splicing-dependent multiprotein exon junction complex (EJC) that is deposited at splice junctions on mRNAs, as a consequence of pre-mRNA splicing. It may thus be involved in mRNA metabolism associated with splicing. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. |