ACOD1 Polyclonal Antibody
| 规格： | / 20μL / 60μL / 120μL / 200μL |
| 价格： | / ￥420 / ￥1010 / ￥1640 / ￥2365 |
货号：E-AB-19833
宿主: Rabbit
反应性: H,M
应用: WB
Overview
| Synonyms | ACOD1,Aconitate decarboxylase 1,Aconitate decarboxylase,CAD,Cis aconitate decarboxylase,Immune responsive gene 1 protein homolog,Immune-responsive gene 1 protein homolog,Immunoresponsive 1 homolog (mouse),Irg1,IRG1,OC116,OPTB1,TCTIRC7,ACOD1抗体 |
| Swissprot | A6NK06 |
| Source | Rabbit |
| Reactivity | Human, Mouse |
| Immunogen | Synthetic peptide of human ACOD1 |
| Application | WB(Detection kit: E-IR-R304) |
| Recommended dilution | WB,,1:500-1:2000; |
| Concentration | 1.32mg/mL |
| Clonality | Polyclonal |
Properties
| Isotype | IgG |
| Purification | Affinity purification |
| Conjugation | Unconjugated |
| Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage buffer | PBS with 0.05% NaN3 and 40% Glycerol,pH7.4 |
| Background | Involved in the inhibition of the inflammatory response. Acts as a negative regulator of the Toll-like receptors (TLRs)-mediated inflammatory innate response by stimulating the tumor necrosis factor alpha-induced protein TNFAIP3 expression via reactive oxygen species (ROS) in LPS-tolerized macrophages. Involved in antimicrobial response of innate immune cells; ACOD1-mediated itaconic acid production contributes to the antimicrobial activity of macrophages. Plays a role in the embryo implantation. |
