ACVR1 Polyclonal Antibody
| 规格： | / 20μL / 60μL / 120μL / 200μL |
| 价格： | / ￥420 / ￥1010 / ￥1640 / ￥2365 |
货号：E-AB-14737
宿主: Rabbit
反应性: H,M,R
应用: IHC
Overview
| Synonyms | Activin A receptor type I,Activin A receptor type II like kinase 2,Activin receptor type I,Activin receptor type-1,Activin receptor-like kinase 2,ACTR-I,ACTRI,Acvr1,ACVR1,ACVR1A,ACVRLK2,ALK 2,ALK-2,ALK2,FOP,Hydroxyalkyl protein kinase,Serine/threonine-protein kinase receptor R1,SKR1,TGF-B superfamily receptor type I,TGFB superfamily receptor type I,TSR-I,TSRI,ACVR1抗体 |
| Swissprot | Q04771 |
| Source | Rabbit |
| Reactivity | Human,Mouse,Rat |
| Immunogen | Recombinant protein of human ACVR1 |
| Application | IHC(Detection kit: E-IR-R213) |
| Recommended dilution | IHC,,1:50-1:200 |
| Concentration | 0.6 mg/mL |
| Clonality | Polyclonal |
Properties
| Cellular localization | Membrane. |
| Tissue specificity | Expressed in normal parenchymal cells, endothelial cells, fibroblasts and tumor-derived epithelial cells. |
| Isotype | IgG |
| Purification | Affinity purification |
| Conjugation | Unconjugated |
| Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage buffer | PBS with 0.05% sodium azide, 50% glycerol, PH7.3 |
| Background | Activins are dimeric growth and differentiation factors which belong to the transforming growth factor-beta (TGF-beta) superfamily of structurally related signaling proteins.Activins signal through a heteromeric complex of receptor serine kinases which include at least two type I ( I and IB) and two type II (II and IIB) receptors.These receptors are all transmembrane proteins, composed of a ligand-binding extracellular domain with cysteine-rich region, a transmembrane domain, and a cytoplasmic domain with predicted serine/threonine specificity.Type I receptors are essential for signaling; and type II receptors are required for binding ligands and for expression of type I receptors. |
