ACVR2A Polyclonal Antibody
| 规格： | / 20μL / 60μL / 120μL / 200μL |
| 价格： | / ￥420 / ￥1010 / ￥1640 / ￥2365 |
货号：E-AB-15513
宿主: Rabbit
反应性: H,M,R
应用: WB,IHC
Overview
| Synonyms | Activin A receptor type IIA,Activin receptor type 2A,Activin receptor type IIA,Activin receptor type-2A,ACTR 2,ACTR IIA,ACTR-IIA,ACTR2,ACTRII,ACTRIIA,Acvr 2,Acvr 2A,Acvr2,ACVR2A,AVR2A,OTTHUMP00000197918,ACVR2A抗体 |
| Swissprot | P27037 |
| Source | Rabbit |
| Reactivity | Human,Mouse,Rat |
| Immunogen | Synthetic peptide of human ACVR2A |
| Application | WB(Detection kit: E-IR-R304),IHC(Detection kit: E-IR-R213) |
| Recommended dilution | WB,,1:500-1:2000; |
| Concentration | 1.2 mg/mL |
| Clonality | Polyclonal |
Properties
| Cellular localization | Membrane. |
| Isotype | IgG |
| Purification | Affinity purification |
| Conjugation | Unconjugated |
| Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage buffer | PBS with 0.05% sodium azide, 50% glycerol, PH7.3 |
| Background | This gene encodes activin A type II receptor. Activins are dimeric growth and differentiation factors which belong to the transforming growth factor-beta (TGF-beta) superfamily of structurally related signaling proteins. Activins signal through a heteromeric complex of receptor serine kinases which include at least two type I (I and IB) and two type II (II and IIB) receptors. These receptors are all transmembrane proteins, composed of a ligand-binding extracellular domain with cysteine-rich region, a transmembrane domain, and a cytoplasmic domain with predicted serine/threonine specificity. Type I receptors are essential for signaling, and type II receptors are required for binding ligands and for expression of type I receptors. Type I and II receptors form a stable complex after ligand binding, resulting in phosphorylation of type I receptors by type II receptors. Type II receptors are considered to be constitutively active kinases. |
Images
Western Blot analysis of Human fetal brain tissue using ACVR2A Polyclonal Antibody at dilution of 1:400
Immunohistochemistry of paraffin-embedded Human colon cancer using ACVR2A Polyclonal Antibody at dilution of 1:20
Immunohistochemistry of paraffin-embedded Human ovarian cancer using ACVR2A Polyclonal Antibody at dilution of 1:20
