ADAMTS2 Polyclonal Antibody
规格: | / 20μL / 60μL / 120μL / 200μL |
价格: | / ¥420 / ¥1010 / ¥1640 / ¥2365 |
货号:E-AB-19434
宿主: Rabbit
反应性: H,M
应用: IHC
Overview
Synonyms | A disintegrin and metalloproteinase with thrombospondin motifs 2,A disintegrin like and metalloprotease (reprolysin type) with thrombospondin type 1 motif 2,ADAM metallopeptidase with thrombospondin type 1 motif 2,ADAM TS 2,ADAM TS2,ADAM-TS 2,ADAM-TS2,ADAMTS 3,ADAMTS-2,ADAMTS2,ATS2,EC 3.4.24.14,EDS VIIB,EDS VIIC,hPCPNI,NPI,PC I NP,PC I-NP,PCINP,PCPNI,pNPI,Procollagen I N proteinase,Procollagen I N-proteinase,Procollagen I/II amino propeptide processing enzyme,Procollagen I/II amino propeptide-processing enzyme,Procollagen N endopeptidase,Procollagen N-endopeptidase,ADAMTS2抗体 |
Swissprot | O95450 |
Source | Rabbit |
Reactivity | Human, Mouse |
Immunogen | Synthetic peptide of human ADAMTS2 |
Application | IHC(Detection kit: E-IR-R213) |
Recommended dilution | IHC,,1:30-1:150 |
Concentration | 1.32mg/mL |
Clonality | Polyclonal |
Properties
Cellular localization | Secreted>extracellular space>extracellular matrix. |
Isotype | IgG |
Purification | Affinity purification |
Conjugation | Unconjugated |
Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
Storage buffer | PBS with 0.05% NaN3 and 40% Glycerol,pH7.4 |
Background | This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The enzyme encoded by this gene excises the N-propeptide of type I, type II and type V procollagens. Mutations in this gene cause Ehlers-Danlos syndrome type VIIC, a recessively inherited connective-tissue disorder. Alternative splicing results in multiple transcript variants. |