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ADAMTS2 Polyclonal Antibody

规格: / 20μL / 60μL / 120μL / 200μL
价格: / ¥420 / ¥1010 / ¥1640 / ¥2365

货号:E-AB-19434

宿主: Rabbit

反应性: H,M

应用: IHC

  • 详情
  • Overview

    Synonyms A disintegrin and metalloproteinase with thrombospondin motifs 2,A disintegrin like and metalloprotease (reprolysin type) with thrombospondin type 1 motif 2,ADAM metallopeptidase with thrombospondin type 1 motif 2,ADAM TS 2,ADAM TS2,ADAM-TS 2,ADAM-TS2,ADAMTS 3,ADAMTS-2,ADAMTS2,ATS2,EC 3.4.24.14,EDS VIIB,EDS VIIC,hPCPNI,NPI,PC I NP,PC I-NP,PCINP,PCPNI,pNPI,Procollagen I N proteinase,Procollagen I N-proteinase,Procollagen I/II amino propeptide processing enzyme,Procollagen I/II amino propeptide-processing enzyme,Procollagen N endopeptidase,Procollagen N-endopeptidase,ADAMTS2抗体
    Swissprot O95450
    Source Rabbit
    Reactivity Human, Mouse
    Immunogen Synthetic peptide of human ADAMTS2
    Application IHC(Detection kit: E-IR-R213)
    Recommended dilution IHC,,1:30-1:150
    Concentration 1.32mg/mL
    Clonality Polyclonal

    Properties

    Cellular localization Secreted>extracellular space>extracellular matrix.
    Isotype IgG
    Purification Affinity purification
    Conjugation Unconjugated
    Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
    Storage buffer PBS with 0.05% NaN3 and 40% Glycerol,pH7.4
    Background This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The enzyme encoded by this gene excises the N-propeptide of type I, type II and type V procollagens. Mutations in this gene cause Ehlers-Danlos syndrome type VIIC, a recessively inherited connective-tissue disorder. Alternative splicing results in multiple transcript variants.
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