AF/LE Purified Anti-Human CD11a Antibody[R7-1]
规格: | / 50μg / 500μg / 1mg |
价格: | / ¥760 / ¥3160 / ¥4760 |
货号:E-AB-F12110
货期:咨询
宿主: Mouse
反应性: H
应用: FCM;FA
Overview
Synonyms | CD11A;ITGAL;Integrin alpha-L;LFA-1A |
Swissprot | P20701 |
Source | Mouse |
Reactivity | Human |
Application | FCM;FA |
Recommended dilution | FCM,,2 μg/mL(1×10^5-5×10^5 cells) |
Concentration | 0.5mg/mL |
Clonality | Monoclonal |
Properties
Clone No | R7-1 |
---|---|
Isotype | Mouse IgG1, κ |
Conjugation | Unconjugated |
Storage instructions | This product can be stored at 2-8°C for 12 months. Do not freeze. |
Storage buffer | 0.2 μm filtered in PBS, pH 7.2. Azide Free (AF)/Low Endotoxin (LE): Contains no stabilizers or stabilizers. Endotoxin level is < 2 EU/mg as Determined by LAL gel clotting assay. |
Background | CD11a is a 170-180 kD type I transmembrane glycoprotein also known as LFA-1α chain and integrin αL subunit. CD11a non-covalently associates with integrin β2 (CD18) to form LFA-1. It is expressed on all leukocytes, including B and T lymphocytes, monocytes, macrophages, neutrophils, basophils and eosinophils. It is absent on non-hematopoietic tissues and platelets. CD11a plays a central role in leukocyte cell-cell interactions and is important in lymphocyte costimulation. CD11a/CD18 binds to ICAM-1 (CD54), ICAM-2 (CD102), and ICAM-3 (CD50). |