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AF/LE Purified Anti-Human CD11a Antibody[R7-1]

规格: / 50μg / 500μg / 1mg
价格: / ¥760 / ¥3160 / ¥4760

货号:E-AB-F12110

货期:咨询

宿主: Mouse

反应性: H

应用: FCM;FA

  • 详情
  • Overview

    Synonyms CD11A;ITGAL;Integrin alpha-L;LFA-1A
    Swissprot P20701
    Source Mouse
    Reactivity Human
    Application FCM;FA
    Recommended dilution FCM,,2 μg/mL(1×10^5-5×10^5 cells)
    Concentration 0.5mg/mL
    Clonality Monoclonal

    Properties

    Clone No R7-1
    Isotype Mouse IgG1, κ
    Conjugation Unconjugated
    Storage instructions This product can be stored at 2-8°C for 12 months. Do not freeze.
    Storage buffer 0.2 μm filtered in PBS, pH 7.2. Azide Free (AF)/Low Endotoxin (LE): Contains no stabilizers or stabilizers. Endotoxin level is < 2 EU/mg as Determined by LAL gel clotting assay.
    Background CD11a is a 170-180 kD type I transmembrane glycoprotein also known as LFA-1α chain and integrin αL subunit. CD11a non-covalently associates with integrin β2 (CD18) to form LFA-1. It is expressed on all leukocytes, including B and T lymphocytes, monocytes, macrophages, neutrophils, basophils and eosinophils. It is absent on non-hematopoietic tissues and platelets. CD11a plays a central role in leukocyte cell-cell interactions and is important in lymphocyte costimulation. CD11a/CD18 binds to ICAM-1 (CD54), ICAM-2 (CD102), and ICAM-3 (CD50).
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