AF/LE Purified Anti-Human CD40 Antibody[G28.5]
| 规格: | / 50μg / 500μg / 1mg |
| 价格: | / ¥760 / ¥3160 / ¥4760 |
货号:E-AB-F12140
货期:咨询
宿主: Mouse
反应性: H
应用: FCM
Overview
| Synonyms | Bp50;CD40L receptor;CDw40;TNFRSF5 |
| Swissprot | P25942 |
| Source | Mouse |
| Reactivity | Human |
| Immunogen | Recombinant Human CD40 protein |
| Application | FCM |
| Recommended dilution | FCM,,2 μg/mL(1×10^5-5×10^5 cells) |
| Concentration | 1mg/mL |
| Clonality | Monoclonal |
Properties
| Clone No | G28.5 |
|---|---|
| Isotype | Mouse IgG1, κ |
| Purification | >98%, Protein A/G purified |
| Conjugation | Unconjugated |
| Storage instructions | Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles. This preparation contains no preservatives, thus it should be handled under aseptic conditions. |
| Storage buffer | Sterile PBS. < 1.0 EU per mg of the antibody as determined by the LAL method |
| Background | CD40 is a 48 kD type I glycoprotein also known as BP50. It is a member of the TNFR superfamily primarily expressed on B cells, macrophages, follicular dendritic cells, endothelial cells, fibroblasts, and at low levels on plasma cells. CD40 has been reported to be involved in B cell differentiation, costimulation, isotype class-switching, and protection of B cells from apoptosis. Additionally, CD40 is important for T cell-B cell interactions. The ligand of CD40 is CD154 (CD40 ligand). |
