AF/LE Purified Anti-Human/Monkey CD154/CD40L Antibody[5C8]
规格: | / 50μg / 500μg / 1mg |
价格: | / ¥760 / ¥3160 / ¥4760 |
货号:E-AB-F11280
货期:咨询
宿主: Mouse
反应性: H;MK
应用: FCM;Block
Overview
Synonyms | T-BAM; TNFSF5; TRAP; gp39;CD40L |
Swissprot | P29965 |
Source | Mouse |
Reactivity | Human;Monkey |
Application | FCM;Block |
Concentration | 0.5mg/mL |
Clonality | Monoclonal |
Properties
Clone No | 5C8 |
---|---|
Isotype | Mouse IgG2a, κ |
Conjugation | Unconjugated |
Storage instructions | This product can be stored at 2-8°C for 12 months. Do not freeze. |
Storage buffer | 0.2 μm filtered in PBS, pH 7.2. Azide Free (AF)/Low Endotoxin (LE): Contains no stabilizers or stabilizers. Endotoxin level is < 2 EU/mg as Determined by LAL gel clotting assay. |
Background | CD154 (CD40 ligand) is also known as CD40L, gp39, TRAP and T-BAM. CD40 ligand is a 32-39 kD type II transmembrane glycoprotein. It is a member of the TNF superfamily and is expressed on activated T cells. It has been reported to be important for B cell costimulation following binding of its receptor, CD40. Additionally, binding of CD40L to CD40 on B cells promotes the secretion of immunoglobulin and Ig isotype switching. CD40L is also involved in the regulation of cytokine production by T cells. |