AF/LE Purified Anti-Mouse CD183/CXCR3 Antibody[CXCR3-173]
| 规格： | / 50μg / 500μg / 1mg |
| 价格： | / ￥760 / ￥3160 / ￥4760 |
货号：E-AB-F11140
货期：咨询
宿主: Armenian Hamster
反应性: M
应用: FCM;Block
Overview
| Synonyms | C-X-C chemokine receptor type 3;CD183/CXCR3;CXC-R3;CXCR-3;Cxcr3;IP-10 receptor;Interferon-inducible protein 10 receptor |
| Swissprot | O88410 |
| Source | Armenian Hamster |
| Reactivity | Mouse |
| Application | FCM;Block |
| Recommended dilution | FCM,,2 μg/mL(1×10^5-5×10^5 cells) |
| Concentration | 0.5mg/mL |
| Clonality | Monoclonal |
Properties
| Clone No | CXCR3-173 |
|---|---|
| Isotype | Armenian Hamster IgG |
| Conjugation | Unconjugated |
| Storage instructions | This product can be stored at 2-8°C for 12 months. Do not freeze. |
| Storage buffer | 0.2 μm filtered in PBS, pH 7.2. Azide Free (AF)/Low Endotoxin (LE): Contains no stabilizers or stabilizers. Endotoxin level is < 2 EU/mg as Determined by LAL gel clotting assay. |
| Background | CD183/CXCR3, also known as CXCR3, is a member of the C-X-C chemokine family, characterized by a pair of cysteine residues separated by a single amino acid. CXCR3 is a 38 kD seven pass transmembrane receptor coupled to G-protein. It mediates Ca2+ mobilization and chemotaxis in response to C-X-C chemokines, such as IP10 (CXCL10), MIG (CXCL9), I-TAC (CXCL11) and PF4 (CXCL4). CXCR3 is expressed primarily on activiated T lymphocytes, NK cells, and some epithelial cells and endothelial cells. It is not expressed on B cells, monocytes or granulocytes. |
