AF/LE Purified Anti-Mouse CD3ε Antibody[145-2C11]
| 规格： | / 50μg / 500μg / 1mg |
| 价格： | / ￥600 / ￥1960 / ￥3560 |
货号：E-AB-F11030
货期：咨询
宿主: Armenian Hamster
反应性: M
应用: FCM
Overview
| Synonyms | CD3E;CD3e;T-cell surface antigen T3/Leu-4 epsilon chain;T-cell surface glycoprotein CD3 epsilon chain;T3E |
| Swissprot | P22646 |
| Source | Armenian Hamster |
| Reactivity | Mouse |
| Immunogen | Recombinant Mouse CD3ε protein |
| Application | FCM |
| Recommended dilution | FCM,,2 μg/mL(1×10^5-5×10^5 cells) |
| Concentration | 1mg/mL |
| Clonality | Monoclonal |
Properties
| Clone No | 145-2C11 |
|---|---|
| Isotype | Armenian Hamster IgG |
| Purification | >98%, Protein A/G purified |
| Conjugation | Unconjugated |
| Storage instructions | Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles. This preparation contains no preservatives, thus it should be handled under aseptic conditions. |
| Storage buffer | Sterile PBS. < 1.0 EU per mg of the antibody as determined by the LAL method |
| Background | CD3ε is a 20 kD transmembrane protein, also known as CD3 or T3. It is a member of the Ig superfamily and primarily expressed on T cells, NK-T cells, and at different levels on thymocytes during T cell differentiation. CD3ε forms a TCR complex by associating with the CD3δ, γ and ζ chains, as well as the TCR α/β or γ/δ chains. CD3 plays a critical role in TCR signal transduction, T cell activation, and antigen recognition by binding the peptide/MHC antigen complex. |
