AF/LE Purified Anti-Mouse TCR γ/δ Antibody[UC7-13D5]
| 规格： | / 50μg / 500μg / 1mg |
| 价格： | / ￥600 / ￥1960 / ￥3560 |
货号：E-AB-F11240
货期：咨询
宿主: Armenian Hamster
反应性: M
应用: FCM
Overview
| Synonyms | γ/δ TCR;TCR-γ/δ |
| Source | Armenian Hamster |
| Reactivity | Mouse |
| Application | FCM |
| Concentration | 0.5mg/mL |
| Clonality | Monoclonal |
Properties
| Clone No | UC7-13D5 |
|---|---|
| Isotype | Armenian Hamster IgG |
| Conjugation | Unconjugated |
| Storage instructions | This product can be stored at 2-8°C for 12 months. Do not freeze. |
| Storage buffer | 0.2 μm filtered in PBS, pH 7.2. Azide Free (AF)/Low Endotoxin (LE): Contains no stabilizers or stabilizers. Endotoxin level is < 2 EU/mg as Determined by LAL gel clotting assay. |
| Background | T cell receptor (TCR) is a heterodimer consisting of an α and a β chain (TCR α/β) or a γ and a δ chain (TCR γ/δ). TCR γ/δ belongs to the immunoglobulin superfamily, involved in the recognition of certain bacterial and tumor antigens bound to MHC class I. The TCR γ/δ associates with CD3 and is expressed on a T cell subset found in the thymus, the intestinal epithelium, and the peripheral lymphoid tissues and peritoneum. Most γ/δ T cells are CD4-/CD8-, some are CD8+. T cells expressing the TCR γ/δ have been shown to play a role in oral tolerance, tumor-associated tolerance, and autoimmune disease. It has been reported that γ/δ T cells also play a principal role in antigen presentation. Immobilized UC7-13D5 antibody has been reported to activate TCR-γ/δ-bearing T cells in vitro, and to deplete peripheral TCR-γ/δ-bearing T cells in vivo. |
