AF/LE Purified Human Anti-CD123 Monoclonal Antibody[6H6]
| 规格： | / 25μg / 100μg |
| 价格： | / ￥300 / ￥700 |
货号：E-AB-F11170P
货期：咨询
宿主: Mouse
反应性: H
应用: FCM
Overview
| Synonyms | CD123;CD123 antigen;hIL 3Ra;hIL-3Ra;hIL3Ra;IL 3 receptor alpha SP2 isoform;IL 3R alpha;IL-3 receptor subunit alpha;IL-3R subunit alpha;IL-3R-alpha;IL-3RA;IL3 Receptor alpha;IL3R;Il3ra;IL3RA;IL3RAX;IL3RAY;IL3RX;IL3RY;Interleukin 3 receptor alpha chain;Interleukin 3 receptor;alpha (low affinity);Interleukin 3 receptor;alpha;Interleukin-3 Receptor alpha;Interleukin-3 receptor subunit alpha;Interleukin3 receptor;Interleukin3 receptor;Y-chromosomal |
| Swissprot | P26951 |
| Source | Mouse |
| Reactivity | Human |
| Immunogen | Recombinant Human CD123 protein |
| Application | FCM |
| Recommended dilution | FCM,,0.2 μg(1×10^5-5×10^5 cells) |
| Concentration | 1mg/mL |
| Clonality | Recombinant |
Properties
| Clone No | 6H6 |
|---|---|
| Isotype | Mouse IgG1, κ |
| Purification | >98%, Protein A/G purified |
| Conjugation | Unconjugated |
| Storage instructions | Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles. This preparation contains no preservatives, thus it should be handled under aseptic conditions. |
| Storage buffer | Sterile PBS. < 1.0 EU per mg of the antibody as determined by the LAL method |
| Background | The protein encoded by this gene is an interleukin 3 specific subunit of a heterodimeric cytokine receptor. The receptor is comprised of a ligand specific alpha subunit and a signal transducing beta subunit shared by the receptors for interleukin 3 (IL3), colony stimulating factor 2 (CSF2/GM-CSF), and interleukin 5 (IL5). The binding of this protein to IL3 depends on the beta subunit. The beta subunit is activated by the ligand binding, and is required for the biological activities of IL3. This gene and the gene encoding the colony stimulating factor 2 receptor alpha chain (CSF2RA) form a cytokine receptor gene cluster in a X-Y pseudoautosomal region on chromosomes X or Y. Alternatively spliced transcript variants encoding distinct isoforms have been found. |
