AF/LE Purified Human Anti-CD54 Monoclonal Antibody[RR1/1]
| 规格： | / 25μg / 100μg |
| 价格： | / ￥300 / ￥700 |
货号：AN003500P
货期：咨询
宿主: Mouse
反应性: H
应用: FCM
Overview
| Synonyms | Intercellular adhesion molecule 1;Icam1;MALA-2;MyD10;CD54;Icam-1 |
| Swissprot | P05362 |
| Source | Mouse |
| Reactivity | Human |
| Immunogen | Recombinant Human CD54 protein |
| Application | FCM |
| Recommended dilution | FCM,,0.2 μg(1×10^5-5×10^5 cells) |
| Concentration | 1mg/mL |
| Clonality | Recombinant |
Properties
| Clone No | RR1/1 |
|---|---|
| Isotype | Mouse IgG2a, κ |
| Purification | >98%, Protein A/G purified |
| Conjugation | Unconjugated |
| Storage instructions | Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles. This preparation contains no preservatives, thus it should be handled under aseptic conditions. |
| Storage buffer | Sterile PBS. < 1.0 EU per mg of the antibody as determined by the LAL method |
| Background | CD54 is a 85-110 kD type I transmembrane protein also known as ICAM-1. It is expressed on activated endothelial cells,high endothelial venules,T and B cells,monocytes/macrophages,granulocytes,and dendritic cells. The expression of ICAM-1 can be released from the cell surface. CD54 plays a role in cellular adhesion and is involved in inflammation and leukocyte extravasation. CD54 has also been shown to be the major cellular receptor for rhinovirus. ICAM-1 binds to CD11a/CD18 (LFA-1),CD11b/CD18 (Mac-1),CD11c/CD18 (p150,95) as well as hyaluronan and fibrinogen. |
