AHR Polyclonal Antibody
| 规格： | / 20μL / 60μL / 120μL / 200μL |
| 价格： | / ￥420 / ￥1010 / ￥1640 / ￥2365 |
货号：E-AB-16242
宿主: Rabbit
反应性: H,M,R
应用: IHC
Overview
| Synonyms | Ah receptor,AhR,AHR,Aromatic hydrocarbon receptor,Aryl hydrocarbon receptor,Aryl hydrocarbon receptor precursor,bHLHe76,Class E basic helix loop helix protein 76,Class E basic helix-loop-helix protein 76,HGNC:348,AHR抗体 |
| Swissprot | P35869 |
| Source | Rabbit |
| Reactivity | Human,Mouse,Rat |
| Immunogen | Synthetic peptide of human AHR |
| Application | IHC(Detection kit: E-IR-R213) |
| Recommended dilution | IHC,,1:25-1:100 |
| Concentration | 0.4 mg/mL |
| Clonality | Polyclonal |
Properties
| Cellular localization | Cytoplasm. Nucleus. Initially cytoplasmic; upon binding with ligand and interaction with a HSP90, it translocates to the nucleus. |
| Tissue specificity | Expressed in all tissues tested including blood, brain, heart, kidney, liver, lung, pancreas and skeletal muscle. |
| Isotype | IgG |
| Purification | Affinity purification |
| Conjugation | Unconjugated |
| Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage buffer | PBS with 0.05% sodium azide, 50% glycerol, PH7.3 |
| Background | This gene encodes a ligand-activated transcription factor involved in the regulation of biological responses to planar aromatic hydrocarbons. This receptor has been shown to regulate xenobiotic-metabolizing enzymes such as cytochrome P450. Its ligands included a variety of aromatic hydrocarbons. |
