AKT2 Polyclonal Antibody
| 规格： | / 20μL / 60μL / 120μL / 200μL |
| 价格： | / ￥420 / ￥1010 / ￥1640 / ￥2365 |
货号：E-AB-16142
宿主: Rabbit
反应性: H,M,R
应用: IHC
Overview
| Synonyms | Akt2,AKT2,HIHGHH,murine thymoma viral (v-akt) homolog-2,PKB,PKB beta,PKBB,PKBBETA,PRKBB,Protein kinase Akt 2,Protein kinase Akt-2,Protein kinase B beta,rac protein kinase beta,RAC-BETA,RAC-beta serine/threonine-protein kinase,RAC-PK-beta,v akt murine thymoma viral oncogene homolog 2,AKT2抗体 |
| Swissprot | P31751 |
| Source | Rabbit |
| Reactivity | Human,Mouse,Rat |
| Immunogen | Synthetic peptide of human AKT2 |
| Application | IHC(Detection kit: E-IR-R213) |
| Recommended dilution | IHC,,1:50-1:200 |
| Concentration | 0.4 mg/mL |
| Clonality | Polyclonal |
Properties
| Cellular localization | Cytosol,Endosome,early endosome,Nucleus,nucleoplasm,nucleus,Plasma Membrane,ruffle membrane,Other locations:cell cortex,intracellular membrane-bounded organelle,protein complex |
| Tissue specificity | Expressed in all human cell types so far analyzed. |
| Isotype | IgG |
| Purification | Affinity purification |
| Conjugation | Unconjugated |
| Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage buffer | PBS with 0.05% sodium azide, 50% glycerol, PH7.3 |
| Background | This gene is a putative oncogene encoding a protein belonging to a subfamily of serine/threonine kinases containing SH2-like (Src homology 2-like) domains. The gene was shown to be amplified and overexpressed in 2 of 8 ovarian carcinoma cell lines and 2 of 15 primary ovarian tumors. Overexpression contributes to the malignant phenotype of a subset of human ductal pancreatic cancers. The encoded protein is a general protein kinase capable of phophorylating several known proteins. |
