ALDH5A1 Polyclonal Antibody
| 规格： | / 20μL / 60μL / 120μL / 200μL |
| 价格： | / ￥420 / ￥1010 / ￥1640 / ￥2365 |
货号：E-AB-12961
宿主: Rabbit
反应性: H,M,R
应用: IHC
Overview
| Synonyms | Aldedehyde dehydrogenase 5 family,Aldehyde dehydrogenase 5 family member A1,Aldehyde dehydrogenase 5A1,Aldehyde dehydrogenase family 5 member A1,ALDH5A 1,Aldh5a1,mitochondrial,Mitochondrial succinate semialdehyde dehydrogenase,NAD(+) dependent succinic semialdehyde dehydrogenase,NAD(+)-dependent succinic semialdehyde dehydrogenase,SSADH,SSDH,SSDH,Succinate semialdehyde dehydrogenase,Succinate-semialdehyde dehydrogenase,ALDH5A1抗体 |
| Swissprot | P51649 |
| Source | Rabbit |
| Reactivity | Human,Mouse,Rat |
| Immunogen | Synthetic peptide of human ALDH5A1 |
| Application | IHC(Detection kit: E-IR-R213) |
| Recommended dilution | IHC,,1:50-1:200 |
| Concentration | 0.5 mg/mL |
| Clonality | Polyclonal |
Properties
| Cellular localization | Mitochondrion. |
| Tissue specificity | Brain, pancreas, heart, liver, skeletal muscle and kidney. Lower in placenta. |
| Isotype | IgG |
| Purification | Affinity purification |
| Conjugation | Unconjugated |
| Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage buffer | PBS with 0.05% sodium azide, 50% glycerol, PH7.3 |
| Background | This protein belongs to the aldehyde dehydrogenase family of proteins. This gene encodes a mitochondrial NAD(+)-dependent succinic semialdehyde dehydrogenase. A deficiency of this enzyme, known as 4-hydroxybutyricaciduria, is a rare inborn error in the metabolism of the neurotransmitter 4-aminobutyric acid (GABA). In response to the defect, physiologic fluids from patients accumulate GHB, a compound with numerous neuromodulatory properties. Two transcript variants encoding distinct isoforms have been identified for this gene. |
