alpha-Synuclein/SNCA Monoclonal Antibody(Capture)
| 规格: | / 25μg / 100μg |
| 价格: | / ¥800 / ¥2100 |
货号:AN002340P
货期:咨询
宿主: Rat
反应性: H
应用: ELISA Capture
Overview
| Synonyms | SNC-A;aSYN;PD1;NACP;PARK1;PARK4; |
| Swissprot | P37840 |
| Source | Rat |
| Reactivity | Human |
| Immunogen | Recombinant Human alpha-Synuclein/SNCA protein expressed by E.coli |
| Application | ELISA Capture |
| Recommended dilution | ELISA Capture,,2-8 μg/mL |
| Concentration | 1mg/mL |
| Clonality | Monoclonal |
Properties
| Clone No | 6B2 |
|---|---|
| Isotype | IgM |
| Purification | Protein A/G Purification |
| Conjugation | Unconjugated |
| Storage instructions | Store at 4°C Valid for 1 month or -20°C Valid for 12 months,Avoid freeze / thaw cycles. This preparation contains no preservatives, thus it should be handled under aseptic conditions. |
| Storage buffer | Sterile PBS,pH 7.4 |
| Background | Alpha-synuclein is a member of the synuclein family, which also includes beta- and gamma-synuclein. Synucleins are abundantly expressed in the brain and alpha- and beta-synuclein inhibit phospholipase D2 selectively. SNCA may serve to integrate presynaptic signaling and membrane trafficking. Defects in SNCA have been implicated in the pathogenesis of Parkinson disease. SNCA peptides are a major component of amyloid plaques in the brains of patients with Alzheimer's disease. Four alternatively spliced transcripts encoding two different isoforms have been identified for this gene. |
