AP1B1 Polyclonal Antibody
规格: | / 20μL / 60μL / 120μL / 200μL |
价格: | / ¥420 / ¥1010 / ¥1640 / ¥2365 |
货号:E-AB-15476
宿主: Rabbit
反应性: H,M,R
应用: IHC
Overview
Synonyms | ADTB1,BAM22,AP105A,CLAPB2,AP1B1抗体 |
Swissprot | Q10567 |
Source | Rabbit |
Reactivity | Human,Mouse,Rat |
Immunogen | Synthetic peptide of human AP1B1 |
Application | IHC(Detection kit: E-IR-R213) |
Recommended dilution | IHC,,1:50-1:200 |
Concentration | 0.6 mg/mL |
Clonality | Polyclonal |
Properties
Cellular localization | Cytosol,Golgi apparatus,Golgi apparatus,Golgi membrane,trans-Golgi network membrane,Lysosome,lysosomal membrane,Other locations:clathrin adaptor complex,clathrin-coated endocytic vesicle membrane,cytoplasmic vesicle membrane,intracellular membrane-bounded organelle |
Tissue specificity | Widely expressed. |
Isotype | IgG |
Purification | Affinity purification |
Conjugation | Unconjugated |
Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
Storage buffer | PBS with 0.05% sodium azide, 50% glycerol, PH7.3 |
Background | Adaptor protein complex 1 is found at the cytoplasmic face of coated vesicles located at the Golgi complex, where it mediates both the recruitment of clathrin to the membrane and the recognition of sorting signals within the cytosolic tails of transmembrane receptors. This complex is a heterotetramer composed of two large, one medium, and one small adaptin subunit. The protein encoded by this gene serves as one of the large subunits of this complex and is a member of the adaptin protein family. This gene is a candidate meningioma gene. Alternative splicing results in multiple transcript variants. |