APBA2 Polyclonal Antibody
| 规格： | / 20μL / 60μL / 120μL / 200μL |
| 价格： | / ￥420 / ￥1010 / ￥1640 / ￥2365 |
货号：E-AB-12975
宿主: Rabbit
反应性: H
应用: IHC
Overview
| Synonyms | Adapter protein X11beta,Amyloid beta A4 precursor protein-binding family A member 2,APBA2,APBA2,D15S1518E,HsT16821,LIN 10,MGC:14091,MGC99508,Mint 2,Mint-2,MINT2,Neuron-specific X11L protein,Neuronal Munc18-1-interacting protein 2,Phosphotyrosine binding/interacting domain (PTB) bearing protein,X11 beta,X11 like protein,X11l,APBA2抗体 |
| Swissprot | Q99767 |
| Source | Rabbit |
| Reactivity | Human |
| Immunogen | Synthetic peptide of human APBA2 |
| Application | IHC(Detection kit: E-IR-R213) |
| Recommended dilution | IHC,,1:100-1:300 |
| Concentration | 0.6 mg/mL |
| Clonality | Polyclonal |
Properties
| Cellular localization | Plasma Membrane,Other locations:synaptic vesicle |
| Tissue specificity | Brain. |
| Isotype | IgG |
| Purification | Affinity purification |
| Conjugation | Unconjugated |
| Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage buffer | PBS with 0.05% sodium azide, 50% glycerol, PH7.3 |
| Background | The protein encoded by this gene is a member of the X11 protein family.It is a neuronal adapter protein that interacts with the Alzheimer's disease amyloid precursor protein (APP).It stabilizes APP and inhibits production of proteolytic APP fragments including the A beta peptide that is deposited in the brains of Alzheimer's disease patients.This gene product is believed to be involved in signal transduction processes.It is also regarded as a putative vesicular trafficking protein in the brain that can form a complex with the potential to couple synaptic vesicle exocytosis to neuronal cell adhesion.Multiple transcript variants encoding different isoforms have been found for this gene. |
