AQP3 Polyclonal Antibody
| 规格： | / 60μL / 120μL / 200μL |
| 价格： | / ￥1380 / ￥2220 / ￥3300 |
货号：E-AB-70279
宿主: Rabbit
反应性: H,M,R
应用: IHC
Overview
| Synonyms | AQP 3,AQP-3,Aqp3,AQP3,Aquaglyceroporin-3,Aquaporin 3 (GIL blood group),Aquaporin 3 (Gill blood group),Aquaporin-3,Aquaporin3,GIL,Gill blood group,AQP3抗体 |
| Swissprot | Q92482,P47862,Q8R2N1 |
| Source | Rabbit |
| Reactivity | Human,Mouse,Rat |
| Immunogen | KLH conjugated Synthetic peptide corresponding to rat Aquaporin 3 |
| Application | IHC(Detection kit: E-IR-R213) |
| Recommended dilution | IHC,,1:200-1:800 |
| Concentration | 1.2 mg/mL |
| Clonality | Polyclonal |
Properties
| Cellular localization | Basolateral cell membrane. In collecting ducts of kidney. |
| Tissue specificity | Widely expressed in epithelial cells of kidney (collecting ducts) and airways, in keratinocytes, immature dendritic cells and erythrocytes. Isoform 2 is not detectable in erythrocytes at the protein level.Highest expression level in nasal cavity epithelium. |
| Isotype | IgG |
| Purification | Affinity purification |
| Conjugation | Unconjugated |
| Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage buffer | PBS with 0.02% sodium azide,100 μg/ml BSA and 50% glycerol. |
| Background | This gene encodes the water channel protein aquaporin 3.Aquaporins are a family of small integral membrane proteins related to the major intrinsic protein, also known as aquaporin 0.Aquaporin 3 is localized at the basal lateral membranes of collecting duct cells in the kidney.In addition to its water channel function, aquaporin 3 has been found to facilitate the transport of nonionic small solutes such as urea and glycerol, but to a smaller degree.It has been suggested that water channels can be functionally heterogeneous and possess water and solute permeation mechanisms. |
Images
Immunohistochemistry analysis of paraffin-embedded human kidney using AQP3 Polyclonal Antibody at dilution of 1:300.
Immunohistochemistry analysis of paraffin-embedded mouse kidney using AQP3 Polyclonal Antibody at dilution of 1:300.
Immunohistochemistry analysis of paraffin-embedded rat kidney using AQP3 Polyclonal Antibody at dilution of 1:300.
