AQP4 Polyclonal Antibody
| 规格： | / 60μL / 120μL / 200μL |
| 价格： | / ￥1380 / ￥2220 / ￥3300 |
货号：E-AB-70277
宿主: Rabbit
反应性: R
应用: IHC
Overview
| Synonyms | AQP 4,AQP-4,AQP4,AQP4,Aquaporin type 4,Aquaporin-4,Aquaporin4,HMIWC 2,HMIWC2,Mercurial insensitive water channel,Mercurial-insensitive water channel,MGC22454,MIWC,WCH 4,WCH4,AQP4抗体 |
| Swissprot | P47863 |
| Source | Rabbit |
| Reactivity | Rat |
| Immunogen | KLH conjugated Synthetic peptide corresponding to rat Aquaporin 4 |
| Application | IHC(Detection kit: E-IR-R213) |
| Recommended dilution | IHC,,1:200-1:800 |
| Concentration | 1.5 mg/mL |
| Clonality | Polyclonal |
Properties
| Cellular localization | Membrane. |
| Tissue specificity | Detected in cerebellum. Detected on pericapillary astrocyte endfeet in cerebellum, and in skeletal muscle. Detected in glial lamellae in the hypothalamus (at protein level). Abundant in mature brain cortex, cerebellum and spinal cord. Highly expressed in the ependymal cell lining the aqueductal system and over the space of the brain in contact with the subarachnoid space. Detected in paraventricular and supraoptic nuclei, the granule cell layer of the dentate gyrus and the Purkinje cell layer in the cerebellum. Only weakly detectable in eye, kidney, intestine, and lung.Highest expression level in brain. |
| Isotype | IgG |
| Purification | Affinity purification |
| Conjugation | Unconjugated |
| Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage buffer | PBS with 0.02% sodium azide,100 μg/ml BSA and 50% glycerol. |
| Background | This gene encodes a member of the aquaporin family of intrinsic membrane proteins that function as water-selective channels in the plasma membranes of many cells. The encoded protein is the predominant aquaporin found in brain. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. |
