AQP4 Polyclonal Antibody
| 规格： | / 60μL / 120μL / 200μL |
| 价格： | / ￥1380 / ￥2220 / ￥3300 |
货号：E-AB-70385
宿主: Rabbit
反应性: M,R
应用: IHC
Overview
| Synonyms | AQP 4,AQP-4,AQP4,AQP4,Aquaporin type 4,Aquaporin-4,Aquaporin4,HMIWC 2,HMIWC2,Mercurial insensitive water channel,Mercurial-insensitive water channel,MGC22454,MIWC,WCH 4,WCH4,AQP4抗体 |
| Swissprot | P55088,P47863 |
| Source | Rabbit |
| Reactivity | Mouse,Rat |
| Immunogen | Recombinant protein corresponding to Mouse Aquaporin 4. |
| Application | IHC(Detection kit: E-IR-R213) |
| Recommended dilution | IHC,,1:500-1:2000; |
| Concentration | 0.6 mg/mL |
| Clonality | Polyclonal |
Properties
| Cellular localization | Membrane. |
| Tissue specificity | Detected in brain cortex, especially around cortical blood vessels, and subjacent to pia, with lower levels in parenchymal membranes . Detected in ependymal and astroglial cells in brain. Detected in supporting Hensen's cells, inner sulcus cells and Claudius cells in the inner ear . Detected in skeletal muscle. Detected in gastric parietal cells. Detected in principal cells in collecting ducts in kidney medulla (at protein level). Detected in brain, heart and skeletal muscle. |
| Isotype | IgG |
| Purification | Affinity purification |
| Conjugation | Unconjugated |
| Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage buffer | PBS with 0.02% sodium azide,100 μg/ml BSA and 50% glycerol. |
| Background | This gene encodes a member of the aquaporin family of intrinsic membrane proteins that function as water-selective channels in the plasma membranes of many cells. The encoded protein is the predominant aquaporin found in brain. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. |
