ARHGEF6 Polyclonal Antibody
| 规格： | / 20μL / 60μL / 120μL / 200μL |
| 价格： | / ￥420 / ￥1010 / ￥1640 / ￥2365 |
货号：E-AB-16170
宿主: Rabbit
反应性: H,M,R
应用: IHC
Overview
| Synonyms | Alpha Pix,Alpha-Pix,ARHG6,ARHGEF6,COOL 2,COOL-2,COOL2,Mental retardation,X linked 46,MRX46,PAK interacting exchange factor alpha,PAK-interacting exchange factor alpha,PIXA,Rac/Cdc42 guanine exchange factor (GEF) 6,Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6,Rac/Cdc42 guanine nucleotide exchange factor 6,Rho guanine nucleotide exchange factor 6,ARHGEF6抗体 |
| Swissprot | Q15052 |
| Source | Rabbit |
| Reactivity | Human,Mouse,Rat |
| Immunogen | Synthetic peptide of human ARHGEF6 |
| Application | IHC(Detection kit: E-IR-R213) |
| Recommended dilution | IHC,,1:50-1:200 |
| Concentration | 0.7 mg/mL |
| Clonality | Polyclonal |
Properties
| Cellular localization | Cytosol,Other locations:intracellular,lamellipodium |
| Tissue specificity | Ubiquitous. |
| Isotype | IgG |
| Purification | Affinity purification |
| Conjugation | Unconjugated |
| Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage buffer | PBS with 0.05% sodium azide, 50% glycerol, PH7.3 |
| Background | Rho GTPases play a fundamental role in numerous cellular processes that are initiated by extracellular stimuli that work through G protein coupled receptors. The encoded protein belongs to a family of cytoplasmic proteins that activate the Ras-like family of Rho proteins by exchanging bound GDP for GTP. It may form a complex with G proteins and stimulate Rho-dependent signals. This protein is activated by PI3-kinase. Mutations in this gene can cause X-chromosomal non-specific mental retardation. |
