ASIC3 Polyclonal Antibody
| 规格： | / 20μL / 60μL / 120μL / 200μL |
| 价格： | / ￥420 / ￥1010 / ￥1640 / ￥2365 |
货号：E-AB-19330
宿主: Rabbit
反应性: H
应用: IHC
Overview
| Synonyms | ACCN 3,Accn3,ACCN3,Acid sensing ion channel 3,Acid-sensing ion channel 3,Amiloride sensitive cation channel 3,Amiloride sensitive cation channel 3 testis,Amiloride-sensitive cation channel 3,ASIC 3,ASIC3,DRASIC,hASIC 3,hASIC3,hTNaC 1,hTNaC1,Modulatory subunit of ASIC 2a,Modulatory subunit of ASIC2a,Neuronal amiloride sensitive cation channel 3,Neuronal amiloride-sensitive cation channel 3,Proton gated cation channel subunit,SLNAC 1,SLNAC1,Testis sodium channel 1,TNaC 1,TNaC1,ASIC3抗体 |
| Swissprot | Q9UHC3 |
| Source | Rabbit |
| Reactivity | Human |
| Immunogen | Synthetic peptide of human ASIC3 |
| Application | IHC(Detection kit: E-IR-R213) |
| Recommended dilution | IHC,,1:30-1:150 |
| Concentration | 1.2mg/mL |
| Clonality | Polyclonal |
Properties
| Cellular localization | Cell membrane. Cytoplasm. Cell surface expression may be stabilized by interaction with LIN7B and cytoplasmic retention by interaction with DLG4. In part cytoplasmic in cochlea cells. |
| Isotype | IgG |
| Purification | Affinity purification |
| Conjugation | Unconjugated |
| Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage buffer | PBS with 0.05% NaN3 and 40% Glycerol,pH7.4 |
| Background | This gene encodes a member of the degenerin/epithelial sodium channel (DEG/ENaC) superfamily.The members of this family are amiloride-sensitive sodium channels that contain intracellular N and C termini, two hydrophobic transmembrane regions, and a large extracellular loop, which has many cysteine residues with conserved spacing.The member encoded by this gene is an acid sensor and may play an important role in the detection of lasting pH changes.In addition, a heteromeric association between this member and acid-sensing (proton-gated) ion channel 2 has been observed as proton-gated channels sensitive to gadolinium.Alternatively spliced transcript variants have been described. |
