ATG7 Polyclonal Antibody
| 规格： | / 60μL / 120μL / 200μL |
| 价格： | / ￥1380 / ￥2220 / ￥3300 |
货号：E-AB-70288
宿主: Rabbit
反应性: H
应用: IHC
Overview
| Synonyms | 1810013K23Rik,Apg 7,APG7 autophagy 7 like,APG7 autophagy 7-like (S. cerevisiae),APG7 like,APG7,S. cerevisiae,homolog of,APG7-like,APG7L,ATG 7,ATG12-activating enzyme E1 ATG7,ATG7,ATG7 autophagy related 7 homolog (S. cerevisiae),ATG7 autophagy related 7 homolog,ATG7,Atg7l,Autophagy 7,S. cerevisiae,homolog of,Autophagy related protein 7,Autophagy-related 7 (yeast),Autophagy-related protein 7,DKFZp434N0735,GSA 7,GSA7,hAGP7,Ubiquitin activating enzyme E1 like protein,Ubiquitin-activating enzyme E1-like protein,Ubiquitin-like modifier-activating enzyme ATG7,ATG7抗体 |
| Swissprot | O95352,Q9D906 |
| Source | Rabbit |
| Reactivity | Human |
| Immunogen | KLH conjugated Synthetic peptide corresponding to mouse ATG7 |
| Application | IHC(Detection kit: E-IR-R213) |
| Recommended dilution | IHC,,1:200-1:800 |
| Concentration | 1 mg/mL |
| Clonality | Polyclonal |
Properties
| Cellular localization | Cytoplasm. Preautophagosomal structure. Localizes also to discrete punctae along the ciliary axoneme and to the base of the ciliary axoneme. |
| Tissue specificity | Widely expressed, especially in kidney, liver, lymph nodes and bone marrow.Highest expression level in corpus callosum. |
| Isotype | IgG |
| Purification | Affinity purification |
| Conjugation | Unconjugated |
| Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage buffer | PBS with 0.02% sodium azide,100 μg/ml BSA and 50% glycerol. |
| Background | ATG7 (Autophagy Related 7) is a Protein Coding gene. Among its related pathways are Autophagy Pathway and Innate Immune System. GO annotations related to this gene include protein homodimerization activity and ubiquitin activating enzyme activity. This gene encodes an E1-like activating enzyme that is essential for autophagy and cytoplasmic to vacuole transport. The encoded protein is also thought to modulate p53-dependent cell cycle pathways during prolonged metabolic stress. It has been associated with multiple functions, including axon membrane trafficking, axonal homeostasis, mitophagy, adipose differentiation, and hematopoietic stem cell maintenance. Alternative splicing results in multiple transcript variants. |
