ATRN Polyclonal Antibody
规格: | / 20μL / 60μL / 120μL / 200μL |
价格: | / ¥420 / ¥1010 / ¥1640 / ¥2365 |
货号:E-AB-16269
宿主: Rabbit
反应性: H,M,R
应用: IHC
Overview
Synonyms | ATRN,ATRN,attractin 2,Attractin,DPPT L,DPPT-L,KIAA0548,Mahogany homolog,mahogany protein,Mahogany,mouse,homolog of,MGCA,ATRN抗体 |
Swissprot | O75882 |
Source | Rabbit |
Reactivity | Human,Mouse,Rat |
Immunogen | Synthetic peptide of human ATRN |
Application | IHC(Detection kit: E-IR-R213) |
Recommended dilution | IHC,,1:50-1:200 |
Concentration | 1.2mg/mL |
Clonality | Polyclonal |
Properties
Cellular localization | Secreted and Cell membrane. |
Tissue specificity | Isoform 2 is detected in plasma (at protein level). Expressed and secreted by activated T lymphocytes. Expressed at low to moderate levels in peripheral blood leukocytes, spleen, lymph node, tonsil, bone marrow and fetal liver. At very low levels found in thymus. Isoform 2 is the major isoform in peripheral blood leukocytes. |
Isotype | IgG |
Purification | Affinity purification |
Conjugation | Unconjugated |
Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
Storage buffer | PBS with 0.05% sodium azide, 50% glycerol, PH7.3 |
Background | Multiple transcript variants encoding different isoforms exist for this gene. One of the isoforms is a membrane-bound protein with sequence similarity to the mouse mahogany protein, a receptor involved in controlling obesity. The other two isoforms are secreted proteins involved in the initial immune cell clustering during inflammatory responses that may regulate the chemotactic activity of chemokines. |