ATXN3 Polyclonal Antibody
| 规格： | / 20μL / 60μL / 120μL / 200μL |
| 价格： | / ￥420 / ￥1010 / ￥1640 / ￥2365 |
货号：E-AB-52456
宿主: Rabbit
反应性: H
应用: IHC
Overview
| Synonyms | AT3,Ataxin 3,ataxin 3 variant h,ataxin 3 variant m,ataxin 3 variant ref,Ataxin-3,ATX3,ATX3,ATXN3,EC 3.4.22.,JOS,Josephin,Machado Joseph disease (spinocerebellar ataxia 3,olivopontocerebellar ataxia 3,autosomal dominant,ataxin 3),Machado Joseph disease,Machado Joseph disease protein 1,Machado-Joseph disease protein 1,Machado-Joseph disease protein 1 homolog,MJD,MJD gene,MJD1,Olivopontocerebellar ataxia 3,OTTHUMP00000221583,OTTHUMP00000221585,OTTHUMP00000221586,OTTHUMP00000221587,OTTHUMP00000231995,OTTHUMP00000231997,Rsca3,SCA3,SCA3 gene,Spinocerebellar ataxia type 3 protein,ATXN3抗体 |
| Swissprot | P54252 |
| Source | Rabbit |
| Reactivity | Human |
| Immunogen | Fusion protein of human ATXN3 |
| Application | IHC(Detection kit: E-IR-R213) |
| Recommended dilution | IHC,,1:40-1:200 |
| Concentration | 0.4mg/mL |
| Clonality | Polyclonal |
Properties
| Cellular localization | Nucleus matrix. Predominantly nuclear, but not exclusively, inner nuclear matrix. |
| Isotype | IgG |
| Purification | Affinity purification |
| Conjugation | Unconjugated |
| Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage buffer | PBS with 0.05% NaN3 and 40% Glycerol,pH7.4 |
| Background | Machado-Joseph disease, also known as spinocerebellar ataxia-3, is an autosomal dominant neurologic disorder.The protein encoded by this gene contains (CAG)n repeats in the coding region, and the expansion of these repeats from the normal 12-44 to 52-86 is one cause of Machado-Joseph disease.There is a negative correlation between the age of onset and CAG repeat numbers.Alternatively spliced transcript variants encoding different isoforms have been described for this gene. |
