B2M Polyclonal Antibody
规格: | / 20μL / 60μL / 120μL / 200μL |
价格: | / ¥420 / ¥1010 / ¥1640 / ¥2365 |
货号:E-AB-40354
宿主: Rabbit
反应性: M,R
应用: WB
Overview
Synonyms | B2M,B2MG,Beta 2 microglobin,Beta 2 microglobulin,Beta 2 microglobulin precursor,Beta chain of mhc class 1 proteins,Beta chain of MHC class I molecules,Beta-2-microglobulin form pI 5.3,CDABP0092,Hdcma22p,IMD43,B2M抗体 |
Swissprot | P01887 |
Source | Rabbit |
Reactivity | Mouse,Rat |
Immunogen | Recombinant Mouse Beta-2-microglobulin protein |
Application | WB(Detection kit: E-IR-R304) |
Recommended dilution | WB 1:500-1:2000 |
Concentration | 0.18mg/mL |
Clonality | Polyclonal |
Properties
Cellular localization | Secreted |
Isotype | IgG |
Purification | Affinity purification |
Conjugation | Unconjugated |
Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
Storage buffer | PBS with 0.05% Proclin300, 50% glycerol, pH7.3. |
Background | Beta-2-microglobulin (B2M) is a component of MHC class I molecules,which are present on the surface of nearly all nucleated cells. It can be found in body fluids under physiologic conditions as a result of shedding from cell surfaces or intracellular release. B2M has various biological functions,including antigen presentation. Investigations reveal that increased synthesis and release of B2M are present in several malignant diseases. |