BACE2 Polyclonal Antibody
| 规格： | / 20μL / 60μL / 120μL / 200μL |
| 价格： | / ￥420 / ￥1010 / ￥1640 / ￥2365 |
货号：E-AB-53590
宿主: Rabbit
反应性: H,M,R
应用: IHC
Overview
| Synonyms | ALP 56,ALP56,Asp 1,ASP1,ASP21,Aspartic Like Protease 56kDa,Aspartic-like protease 56 kDa,Aspartyl protease 1,BACE 2,Bace2,BACE2,Beta Secretase 2,Beta Site Amyloid Beta A4 Precursor Protein Cleaving Enzyme 2,Beta-secretase 2,Beta-site amyloid precursor protein cleaving enzyme 2,Beta-site APP cleaving enzyme 2,Down region aspartic protease,Downs Syndrome Region Aspartic Protease,DRAP,Memapsin 1,Memapsin-1,Membrane associated aspartic protease 1,Membrane-associated aspartic protease 1,Theta-secretase,BACE2抗体 |
| Swissprot | Q9Y5Z0 |
| Source | Rabbit |
| Reactivity | Human,Mouse,Rat |
| Immunogen | Synthetic peptide of human BACE2 |
| Application | IHC(Detection kit: E-IR-R213) |
| Recommended dilution | IHC,,1:30-1:150 |
| Concentration | 0.8mg/mL |
| Clonality | Polyclonal |
Properties
| Cellular localization | Membrane. Golgi apparatus. Endoplasmic reticulum. Endosome. Cell surface. |
| Isotype | IgG |
| Purification | Affinity purification |
| Conjugation | Unconjugated |
| Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage buffer | PBS with 0.05% NaN3 and 40% Glycerol,pH7.4 |
| Background | This gene encodes an integral membrane glycoprotein that functions as an aspartic protease. The encoded protein cleaves amyloid precursor protein into amyloid beta peptide, which is a critical step in the etiology of Alzheimer's disease and Down syndrome. The protein precursor is further processed into an active mature peptide. Alternative splicing results in multiple transcript variants. |
