BAG2 Polyclonal Antibody
| 规格： | / 60μL / 120μL / 200μL |
| 价格： | / ￥1380 / ￥2220 / ￥3300 |
货号：E-AB-70258
宿主: Rabbit
反应性: R
应用: IHC
Overview
| Synonyms | BAG 2,BAG family molecular chaperone regulator 2,BAG-2,BAG-family molecular chaperone regulator-2,Bag2,BAG2,BCL 2 associated athanogene 2,Bcl-2-associated athanogene 2,BCL2 associated athanogene 2,BCL2-associated athanogene 2,dJ417I1.2 (BAG family molecular chaperone regulator 2),dJ417I1.2,KIAA0576,MGC149462,OTTHUMP00000016668,BAG2抗体 |
| Swissprot | Q91YN9 |
| Source | Rabbit |
| Reactivity | Rat |
| Immunogen | KLH conjugated Synthetic peptide corresponding to Mouse Bag2 |
| Application | IHC(Detection kit: E-IR-R213) |
| Recommended dilution | IHC,,1:200-1:800 |
| Concentration | 0.89 mg/mL |
| Clonality | Polyclonal |
Properties
| Cellular localization | Cytoskeleton,Cytoplasm |
| Tissue specificity | Highest expression level in tracheobronchial tree |
| Isotype | IgG |
| Purification | Affinity purification |
| Conjugation | Unconjugated |
| Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage buffer | PBS with 0.02% sodium azide,100 μg/ml BSA and 50% glycerol. |
| Background | BAG proteins compete with Hip for binding to the Hsc70/Hsp70 ATPase domain and promote substrate release. All the BAG proteins have an approximately 45-amino acid BAG domain near the C terminus but differ markedly in their N-terminal regions. The predicted BAG2 protein contains 211 amino acids. The BAG domains of BAG1, BAG2, and BAG3 interact specifically with the Hsc70 ATPase domain in vitro and in mammalian cells. All 3 proteins bind with high affinity to the ATPase domain of Hsc70 and inhibit its chaperone activity in a Hip-repressible manner. |
