BAG3 Polyclonal Antibody
| 规格： | / 50μL / 100μL |
| 价格： | / ￥1010 / ￥1640 |
货号：E-AB-40660
货期：咨询
宿主: Rabbit
反应性: H,R
应用: WB
Overview
| Synonyms | BAG family molecular chaperone regulator 3 ,BAG-3, Bcl-2-associated athanogene 3, Bcl-2-binding protein Bis, BIS |
| Swissprot | O95817 |
| Source | Rabbit |
| Reactivity | Human,Rat |
| Immunogen | Recombinant Human BAG3 protein expressed by E.coli |
| Application | WB(Detection kit: E-IR-R304) |
| Recommended dilution | WB,,1:500-1:1000; |
| Concentration | 0.4mg/mL |
| Clonality | Polyclonal |
Properties
| Isotype | IgG |
| Purification | Antigen Affinity Purification |
| Conjugation | Unconjugated |
| Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage buffer | PBS with 0.02% sodium azide,1% protective protein and 50% glycerol,pH7.4 |
| Background | Co-chaperone for HSP70 and HSC70 chaperone proteins. Acts as a nucleotide-exchange factor (NEF) promoting the release of ADP from the HSP70 and HSC70 proteins thereby triggering client/substrate protein release. Nucleotide release is mediated via its binding to the nucleotide-binding domain (NBD) of HSPA8/HSC70 where as the substrate release is mediated via its binding to the substrate-binding domain (SBD) of HSPA8/HSC70. |
