BAP1 Polyclonal Antibody
| 规格： | / 20μL / 60μL / 120μL / 200μL |
| 价格： | / ￥420 / ￥1010 / ￥1640 / ￥2365 |
货号：E-AB-52177
宿主: Rabbit
反应性: H,M,R
应用: IHC
Overview
| Synonyms | BAP 1,Bap1,BAP1,BRCA 1 associated protein 1,BRCA1 associated protein 1,BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase),BRCA1-associated protein 1,Cerebral protein 13,Cerebral protein 6,DKFZp686N04275,FLJ35406,FLJ37180,HUCEP 13,Hucep 6,HUCEP13,Hucep6,KIAA0272,TPDS,Ubiquitin carboxy terminal hydrolase,Ubiquitin carboxyl terminal hydrolase BAP 1,Ubiquitin carboxyl terminal hydrolase BAP1,Ubiquitin carboxyl-terminal hydrolase BAP1,UCHL2,BAP1抗体 |
| Swissprot | Q92560 |
| Source | Rabbit |
| Reactivity | Human,Mouse,Rat |
| Immunogen | Fusion protein of human BAP1 |
| Application | IHC(Detection kit: E-IR-R213) |
| Recommended dilution | IHC,,1:40-1:200 |
| Concentration | 0.8mg/mL |
| Clonality | Polyclonal |
Properties
| Cellular localization | Cytoplasm. Nucleus. Mainly nuclear. Binds to chromatin. |
| Isotype | IgG |
| Purification | Affinity purification |
| Conjugation | Unconjugated |
| Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage buffer | PBS with 0.05% NaN3 and 40% Glycerol,pH7.4 |
| Background | This gene belongs to the ubiquitin C-terminal hydrolase subfamily of deubiquitinating enzymes that are involved in the removal of ubiquitin from proteins. The encoded enzyme binds to the breast cancer type 1 susceptibility protein (BRCA1) via the RING finger domain of the latter and acts as a tumor suppressor. In addition, the enzyme may be involved in regulation of transcription, regulation of cell cycle and growth, response to DNA damage and chromatin dynamics. Germline mutations in this gene may be associated with tumor predisposition syndrome (TPDS), which involves increased risk of cancers including malignant mesothelioma, uveal melanoma and cutaneous melanoma. |
客户发表文献
- 文献: Expression levels of BAP1, OGT, and YY1 genes in patients with eyelid tumors
样品类型: BCC tissue
