BCAS4 Polyclonal Antibody
| 规格： | / 20μL / 60μL / 120μL / 200μL |
| 价格： | / ￥420 / ￥1010 / ￥1640 / ￥2365 |
货号：E-AB-16277
宿主: Rabbit
反应性: H
应用: WB,IHC
Overview
| Synonyms | BCAS4,BCAS4/BCAS3 fusion,BCAS4,Breast carcinoma amplified sequence 4,Breast carcinoma amplified sequence 4/3 fusion protein,Breast carcinoma-amplified sequence 4,CNOL,FLJ20495,RP5-1071L10.2,BCAS4抗体 |
| Swissprot | Q8TDM0 |
| Source | Rabbit |
| Reactivity | Human |
| Immunogen | Synthetic peptide of human BCAS4 |
| Application | WB(Detection kit: E-IR-R304),IHC(Detection kit: E-IR-R213) |
| Recommended dilution | WB,,1:500-1:2000;IHC,,1:50-1:200; |
| Concentration | 0.6mg/mL |
| Clonality | Polyclonal |
Properties
| Cellular localization | Cytoplasm. |
| Tissue specificity | Brain, thymus, spleen, kidney and placenta. Overexpressed in most breast cancer cell lines. |
| Isotype | IgG |
| Purification | Affinity purification |
| Conjugation | Unconjugated |
| Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage buffer | PBS with 0.05% sodium azide, 50% glycerol, PH7.3 |
| Background | The gene encoding BCAS4 (Breast carcinoma-amplified sequence 4), a 211 amino acid protein, is found in a region on chromosome 20 that is frequently amplified in human breast cancer.The amplification and translocation between the BCAS4 gene and the BCAS3 gene, with a 17q23 locus, results in a fusion transcript that is overexpressed in MCF-7 cells.Also, deletion of chromosomal region 20q13.13-q13.2 and resultant deletion of BCAS4, as well as three other genes, is the cause of Okihiro syndrome, a disease characterized by ocular and upper limb anomalies. |
Images
Western Blot analysis of Mouse spleen tissue using BCAS4 Polyclonal Antibody at dilution of 1:1200
Immunohistochemistry of paraffin-embedded Human gastic cancer using BCAS4 Polyclonal Antibody at dilution of 1:50
Immunohistochemistry of paraffin-embedded Human thyroid cancer using BCAS4 Polyclonal Antibody at dilution of 1:50
