BCL2 Monoclonal Antibody
规格: | / 20μL / 60μL / 120μL |
价格: | / ¥580 / ¥1420 / ¥2310 |
货号:E-AB-22004
宿主: Mouse
反应性: H,M,R
应用: WB
Overview
Synonyms | Apoptosis regulator Bcl 2,Apoptosis regulator Bcl-2,Apoptosis regulator Bcl2,AW986256,B cell CLL/lymphoma 2,B cell leukemia/lymphoma 2,Bcl-2,Bcl2,BCL2,C430015F12Rik,D630044D05Rik,D830018M01Rik,Leukemia/lymphoma,B-cell,2,Oncogene B-cell leukemia 2,PPP1R50,Protein phosphatase 1,regulatory subunit 50,Bcl-2抗体 |
Swissprot | P10415 |
Source | Mouse |
Reactivity | Human |
Immunogen | Synthetic Peptide |
Application | WB(Detection kit: E-IR-R304) |
Recommended dilution | WB,,1:1000-2000 |
Concentration | 1mg/mL |
Clonality | Monoclonal |
Properties
Cellular localization | Mitochondrion outer membrane. Nucleus membrane. Endoplasmic reticulum membrane. |
Tissue specificity | Expressed in a variety of tissues. |
Clone No | Clone:1B3 |
---|---|
Isotype | IgG |
Purification | Protein A purification |
Conjugation | Unconjugated |
Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
Storage buffer | PBS with 0.02% sodium azide, 50% glycerol, pH7.4 |
Background | Suppresses apoptosis in a variety of cell systems including factor-dependent lymphohematopoietic and neural cells. Regulates cell death by controlling the mitochondrial membrane permeability. Appears to function in a feedback loop system with caspases. Inhibits caspase activity either by preventing the release of cytochrome c from the mitochondria and/or by binding to the apoptosis-activating factor (APAF-1). |
客户发表文献
- 文献: Gastroprotective effect of gallic acid against ethanol-induced gastric ulcer in rats: Involvement of the Nrf2/HO-1 signaling and anti-apoptosis role
样品类型: Tissue - 文献: Royal jelly protects brain tissue against fluoride-induced damage by activating Bcl-2/NF-κB/caspase-3/caspase-6/Bax and Erk signaling pathways in rats
样品类型: Brain tissue - 文献: Tilianin Reduces Apoptosis via the ERK/EGR1/BCL2L1 Pathway in Ischemia/Reperfusion-Induced Acute Kidney Injury Mice.
样品类型: kidney tissue - 文献: Vitamin D3 regulates apoptosis and proliferation in the testis of D-galactose-induced aged rat model
样品类型: testicular - 文献: The anti-cancer effect of flaxseed lignan derivatives on different acute myeloid leukemia cancer cells
样品类型: Cell sample - 文献: Lifelong Football Training: Effects on Autophagy and Healthy Longevity Promotion
样品类型: Tissue homogenate - 文献: Leech therapy (Hirudo medicinalis) attenuates testicular damages induced by testicular ischemia/reperfusion in an animal model
样品类型: testicular