BMP2 Monoclonal Antibody
规格: | / 60μL / 120μL |
价格: | / ¥1420 / ¥2310 |
货号:E-AB-70352
宿主: Mouse
反应性: R
应用: IHC
Overview
Synonyms | BDA2,BMP-2,BMP-2A,Bmp2,BMP2,BMP2A,Bone morphogenetic protein 2,Bone morphogenetic protein 2A,BMP2抗体 |
Swissprot | P12643,P21274,P49001 |
Source | Mouse |
Reactivity | Rat |
Immunogen | Recombinant protein corresponding to Mouse BMP2 |
Application | IHC(Detection kit: E-IR-R213) |
Recommended dilution | IHC,,1:200-1:800 |
Concentration | 2.65 mg/mL |
Clonality | Monoclonal |
Properties
Clone No | 2H6D12 |
---|---|
Isotype | IgG |
Purification | Affinity purification |
Conjugation | Unconjugated |
Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
Storage buffer | PBS with 0.02% sodium azide,100 μg/ml BSA and 50% glycerol. |
Background | Bone morphogenetic protein-2 (BMP-2) is a member of the transforming growth factor-beta (TGFB) superfamily. BMP2 is synthesized as a 60 kDa precursor that is processed in the secretory pathway to a small 18 kDa monomer; 2 monomers then associate to form the active 30 kDa homodimer,which binds to its receptor. There is also a 40-45 kDa form of BMP2,as an amino-terminal propeptide. BMP2 can induce bone formation and regeneration during early embryonic development. It is involved in the hedgehog pathway,TGF beta signaling pathway,and cytokine-cytokine receptor interaction. |