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BMP2 Monoclonal Antibody

规格: / 60μL / 120μL
价格: / ¥1420 / ¥2310

货号:E-AB-70352

宿主: Mouse

反应性: R

应用: IHC

  • 详情
  • Overview

    Synonyms BDA2,BMP-2,BMP-2A,Bmp2,BMP2,BMP2A,Bone morphogenetic protein 2,Bone morphogenetic protein 2A,BMP2抗体
    Swissprot P12643,P21274,P49001
    Source Mouse
    Reactivity Rat
    Immunogen Recombinant protein corresponding to Mouse BMP2
    Application IHC(Detection kit: E-IR-R213)
    Recommended dilution IHC,,1:200-1:800
    Concentration 2.65 mg/mL
    Clonality Monoclonal

    Properties

    Clone No 2H6D12
    Isotype IgG
    Purification Affinity purification
    Conjugation Unconjugated
    Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
    Storage buffer PBS with 0.02% sodium azide,100 μg/ml BSA and 50% glycerol.
    Background Bone morphogenetic protein-2 (BMP-2) is a member of the transforming growth factor-beta (TGFB) superfamily. BMP2 is synthesized as a 60 kDa precursor that is processed in the secretory pathway to a small 18 kDa monomer; 2 monomers then associate to form the active 30 kDa homodimer,which binds to its receptor. There is also a 40-45 kDa form of BMP2,as an amino-terminal propeptide. BMP2 can induce bone formation and regeneration during early embryonic development. It is involved in the hedgehog pathway,TGF beta signaling pathway,and cytokine-cytokine receptor interaction.
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