BMP4 Polyclonal Antibody
规格: | / 60μL / 120μL / 200μL |
价格: | / ¥1380 / ¥2220 / ¥3300 |
货号:E-AB-70376
宿主: Rabbit
反应性: M
应用: IHC
Overview
Synonyms | zgc:100779,BMP 2B,BMP 4,BMP-2B,BMP-4,BMP2B,BMP2B1,BMP4,BMP4,Bone morphogenetic protein 2B,Bone morphogenetic protein 4,DVR4,MCOPS6,MGC100779,OFC11,zbmp-4,ZYME,BMP4抗体 |
Swissprot | P21275,Q06826 |
Source | Rabbit |
Reactivity | Mouse |
Immunogen | Recombinant protein corresponding to Mouse Mouse BMP4. |
Application | IHC(Detection kit: E-IR-R213) |
Recommended dilution | IHC,,1:500-1:2000; |
Concentration | 1.9 mg/mL |
Clonality | Polyclonal |
Properties
Cellular localization | Secreted>extracellular space>extracellular matrix. |
Tissue specificity | Highest expression level in camera-type eye |
Isotype | IgG |
Purification | Affinity purification |
Conjugation | Unconjugated |
Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
Storage buffer | PBS with 0.02% sodium azide,100 μg/ml BSA and 50% glycerol. |
Background | The protein encoded by this gene is a member of the bone morphogenetic protein family which is part of the transforming growth factor-beta superfamily. The superfamily includes large families of growth and differentiation factors. Bone morphogenetic proteins were originally identified by an ability of demineralized bone extract to induce endochondral osteogenesis in vivo in an extraskeletal site. This particular family member plays an important role in the onset of endochondral bone formation in humans, and a reduction in expression has been associated with a variety of bone diseases, including the heritable disorder Fibrodysplasia Ossificans Progressiva. Alternative splicing in the 5' untranslated region of this gene has been described and three variants are described, all encoding an identical protein. |