BNIP3 Polyclonal Antibody
| 规格： | / 60μL / 120μL / 200μL |
| 价格： | / ￥1380 / ￥2220 / ￥3580 |
货号：E-AB-61061
宿主: Rabbit
反应性: H,M,R
应用: IHC,IF
Overview
| Synonyms | BNIP3,NIP3,BNIP3抗体 |
| Swissprot | Q12983 |
| Source | Rabbit |
| Reactivity | Human,Mouse,Rat |
| Immunogen | Recombinant fusion protein of human BNIP3 (NP_004043.3). |
| Application | IHC(Detection kit: E-IR-R213),IF |
| Recommended dilution | IHC,, 1:50-1:200;IF,, 1:50-1:200; |
| Concentration | 1 mg/mL |
| Clonality | Polyclonal |
Properties
| Cellular localization | Mitochondrion. Mitochondrion membrane. Coexpression with the EIB 19-kDa protein results in a shift in NIP3 localization pattern to the nuclear envelope. Colocalizes with ACAA2 in the mitochondria. |
| Isotype | IgG |
| Purification | Affinity purification |
| Conjugation | Unconjugated |
| Storage instructions | Store at -20°C. Avoid freeze / thaw cycles. |
| Storage buffer | PBS with 0.02% sodium azide, 50% glycerol, pH7.3 |
| Background | This gene is encodes a mitochondrial protein that contains a BH3 domain and acts as a pro-apoptotic factor. The encoded protein interacts with anti-apoptotic proteins, including the E1B 19 kDa protein and Bcl2. This gene is silenced in tumors by DNA methylation. |
Images
Immunohistochemistry of paraffin-embedded Mouse kidney using BNIP3 Polyclonal Antibody at dilution of 1:100 (40x lens).
Immunohistochemistry of paraffin-embedded Rat heart using BNIP3 Polyclonal Antibody at dilution of 1:100 (40x lens).
Immunohistochemistry of paraffin-embedded Human liver damage using BNIP3 Polyclonal Antibody at dilution of 1:100 (40x lens).
Immunofluorescence analysis of HeLa cells using BNIP3 Polyclonal Antibody at dilution of 1:100. Blue: DAPI for nuclear staining.
