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BPGM Polyclonal Antibody

规格: / 20μL / 60μL / 120μL / 200μL
价格: / ¥420 / ¥1010 / ¥1640 / ¥2365

货号:E-AB-18543

宿主: Rabbit

反应性: H,M

应用: WB,IHC

  • 详情
  • Overview

    Synonyms 2,2,3-bisphosphoglycerate mutase,2,3-bisphosphoglycerate mutase, erythrocyte,2,3-bisphosphoglycerate synthase,2,3-diphosphoglycerate mutase,3-bisphosphoglycerate mutase,3-bisphosphoglycerate synthase,3-diphosphoglycerate mutase,Ab2 098,AI323730,AL022789,Bisphosphoglycerate mutase,BPG dependent PGAM,BPG-dependent PGAM,Bpgm,C86192,DPGM,Erythrocyte 2,3 bisphosphoglycerate mutase,erythrocyte,PMGE,BPGM抗体
    Swissprot P07738
    Source Rabbit
    Reactivity Human, Mouse
    Immunogen Full length fusion protein
    Application WB(Detection kit: E-IR-R304),IHC(Detection kit: E-IR-R213)
    Recommended dilution WB,,1:1000-1:5000;IHC,,1:50-1:300;
    Concentration 1.1mg/mL
    Clonality Polyclonal

    Properties

    Isotype IgG
    Purification Affinity purification
    Conjugation Unconjugated
    Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
    Storage buffer PBS with 0.05% NaN3 and 40% Glycerol,pH7.4
    Background 2,3-diphosphoglycerate (2,3-DPG) is a small molecule found at high concentrations in red blood cells where it binds to and decreases the oxygen affinity of hemoglobin. This gene encodes a multifunctional enzyme that catalyzes 2,3-DPG synthesis via its synthetase activity, and 2,3-DPG degradation via its phosphatase activity. The enzyme also has phosphoglycerate phosphomutase activity. Deficiency of this enzyme increases the affinity of cells for oxygen. Mutations in this gene result in hemolytic anemia. Multiple alternatively spliced variants, encoding the same protein, have been identified.
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