BPGM Polyclonal Antibody
规格: | / 20μL / 60μL / 120μL / 200μL |
价格: | / ¥420 / ¥1010 / ¥1640 / ¥2365 |
货号:E-AB-18543
宿主: Rabbit
反应性: H,M
应用: WB,IHC
Overview
Synonyms | 2,2,3-bisphosphoglycerate mutase,2,3-bisphosphoglycerate mutase, erythrocyte,2,3-bisphosphoglycerate synthase,2,3-diphosphoglycerate mutase,3-bisphosphoglycerate mutase,3-bisphosphoglycerate synthase,3-diphosphoglycerate mutase,Ab2 098,AI323730,AL022789,Bisphosphoglycerate mutase,BPG dependent PGAM,BPG-dependent PGAM,Bpgm,C86192,DPGM,Erythrocyte 2,3 bisphosphoglycerate mutase,erythrocyte,PMGE,BPGM抗体 |
Swissprot | P07738 |
Source | Rabbit |
Reactivity | Human, Mouse |
Immunogen | Full length fusion protein |
Application | WB(Detection kit: E-IR-R304),IHC(Detection kit: E-IR-R213) |
Recommended dilution | WB,,1:1000-1:5000;IHC,,1:50-1:300; |
Concentration | 1.1mg/mL |
Clonality | Polyclonal |
Properties
Isotype | IgG |
Purification | Affinity purification |
Conjugation | Unconjugated |
Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
Storage buffer | PBS with 0.05% NaN3 and 40% Glycerol,pH7.4 |
Background | 2,3-diphosphoglycerate (2,3-DPG) is a small molecule found at high concentrations in red blood cells where it binds to and decreases the oxygen affinity of hemoglobin. This gene encodes a multifunctional enzyme that catalyzes 2,3-DPG synthesis via its synthetase activity, and 2,3-DPG degradation via its phosphatase activity. The enzyme also has phosphoglycerate phosphomutase activity. Deficiency of this enzyme increases the affinity of cells for oxygen. Mutations in this gene result in hemolytic anemia. Multiple alternatively spliced variants, encoding the same protein, have been identified. |
Images
Western blot analysis of Human placenta tissue lysate using BPGM Polyclonal Antibody at dilution of 1:1350
Immunohistochemistry of paraffin-embedded Human liver cancer tissue using BPGM Polyclonal Antibody at dilution of 1:70(×200)
Immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using BPGM Polyclonal Antibody at dilution of 1:70(×200)