BRI3BP Polyclonal Antibody
| 规格： | / 20μL / 60μL / 120μL / 200μL |
| 价格： | / ￥420 / ￥1010 / ￥1640 / ￥2365 |
货号：E-AB-53455
宿主: Rabbit
反应性: H,M
应用: WB,IHC
Overview
| Synonyms | BNAS1,BRI3 binding protein,BRI3-binding protein,BRI3B,Bri3bp,Cervical cancer 1 proto oncogene binding protein KG19,Cervical cancer 1 proto-oncogene-binding protein KG19,cervical cancer oncogene binding protein,HCCR-2,HCCR1,HCCRBP-1,I3 binding protein,I3-binding protein,KG19,BRI3BP抗体 |
| Swissprot | Q8WY22 |
| Source | Rabbit |
| Reactivity | Human, Mouse |
| Immunogen | Synthetic peptide of human BRI3BP |
| Application | WB(Detection kit: E-IR-R304),IHC(Detection kit: E-IR-R213) |
| Recommended dilution | WB,,1:500-1:2000;IHC,,1:30-1:150; |
| Concentration | 0.9mg/mL |
| Clonality | Polyclonal |
Properties
| Cellular localization | Mitochondrion outer membrane. |
| Isotype | IgG |
| Purification | Affinity purification |
| Conjugation | Unconjugated |
| Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage buffer | PBS with 0.05% NaN3 and 40% Glycerol,pH7.4 |
| Background | BRI3BP (BRI3 binding protein), also known as BNAS1, HCCR-1, I3-binding protein or cervical cancer 1 proto-oncogene-binding protein KG19, is a 251 amino acid multi-pass membrane protein. Though widely expressed, BRI3BP is found at highest levels in brain, kidney and liver where it localizes to the endoplasmic reticulum (ER) and is involved in ER structural dynamics and mitochondrial viability. Possessing pro-apoptotic properties and the ability to potentiate drug-induced apoptosis, BRI3BP overexpression has been shown to enhance caspase-3 and mitochondrial cytochrome c release in etoposide-treated human embryonic kidney 293T cells. |
Images
Western blot analysis of RAW264.7 and K562 cell lysates using BRI3BP Polyclonal Antibody at dilution of 1:500
Immunohistochemistry of paraffin-embedded Human cervical cancer tissue using BRI3BP Polyclonal Antibody at dilution of 1:35(×200)
Immunohistochemistry of paraffin-embedded Human tonsil tissue using BRI3BP Polyclonal Antibody at dilution of 1:35(×200)
