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C14orf2 Polyclonal Antibody

规格: / 20μL / 60μL / 120μL / 200μL
价格: / ¥420 / ¥1010 / ¥1640 / ¥2365

货号:E-AB-19636

宿主: Rabbit

反应性: H,M

应用: WB,IHC

  • 详情
  • Overview

    Synonyms 6.8 kDa mitochondrial proteolipid,68MP,Chromosome 14 open reading frame 2,MP68,PLPM,C14orf2抗体
    Swissprot P56378
    Source Rabbit
    Reactivity Human, Mouse
    Immunogen Synthetic peptide of human C14orf2
    Application WB(Detection kit: E-IR-R304),IHC(Detection kit: E-IR-R213)
    Recommended dilution WB,,1:500-1:2000;IHC,,1:40-1:200;
    Concentration 1.1mg/mL
    Clonality Polyclonal

    Properties

    Cellular localization Mitochondrion.
    Isotype IgG
    Purification Affinity purification
    Conjugation Unconjugated
    Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
    Storage buffer PBS with 0.05% NaN3 and 40% Glycerol,pH7.4
    Background C14orf2, also known as MP68, MP68 is a 58 amino acid mitochondrial protein that belongs to the small mitochondrial proteolipid family. The gene encoding MP68 maps to human chromosome 14, which houses over 700 genes and comprises nearly 3.5% of the human genome. Chromosome 14 encodes the presinilin 1 (PSEN1) gene, which is one of the three key genes associated with the development of Alzheimer's disease (AD). The SERPINA1 gene is also located on chromosome 14 and, when defective, leads to the genetic disorder α1-antitrypsin deficiency, which is characterized by severe lung complications and liver dysfunction.
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