C14orf2 Polyclonal Antibody
规格: | / 20μL / 60μL / 120μL / 200μL |
价格: | / ¥420 / ¥1010 / ¥1640 / ¥2365 |
货号:E-AB-19636
宿主: Rabbit
反应性: H,M
应用: WB,IHC
Overview
Synonyms | 6.8 kDa mitochondrial proteolipid,68MP,Chromosome 14 open reading frame 2,MP68,PLPM,C14orf2抗体 |
Swissprot | P56378 |
Source | Rabbit |
Reactivity | Human, Mouse |
Immunogen | Synthetic peptide of human C14orf2 |
Application | WB(Detection kit: E-IR-R304),IHC(Detection kit: E-IR-R213) |
Recommended dilution | WB,,1:500-1:2000;IHC,,1:40-1:200; |
Concentration | 1.1mg/mL |
Clonality | Polyclonal |
Properties
Cellular localization | Mitochondrion. |
Isotype | IgG |
Purification | Affinity purification |
Conjugation | Unconjugated |
Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
Storage buffer | PBS with 0.05% NaN3 and 40% Glycerol,pH7.4 |
Background | C14orf2, also known as MP68, MP68 is a 58 amino acid mitochondrial protein that belongs to the small mitochondrial proteolipid family. The gene encoding MP68 maps to human chromosome 14, which houses over 700 genes and comprises nearly 3.5% of the human genome. Chromosome 14 encodes the presinilin 1 (PSEN1) gene, which is one of the three key genes associated with the development of Alzheimer's disease (AD). The SERPINA1 gene is also located on chromosome 14 and, when defective, leads to the genetic disorder α1-antitrypsin deficiency, which is characterized by severe lung complications and liver dysfunction. |
Images
Western blot analysis of 293T and RAW264.7 cell Human fetal brain tissue Jurkat and 231 cell Human heart tissue Hela cell lysates using C14orf2 Polyclonal Antibody at dilution of 1:600
Immunohistochemistry of paraffin-embedded Human prost at e cancer tissue using C14orf2 Polyclonal Antibody at dilution of 1:60(×200)
Immunohistochemistry of paraffin-embedded Human brain tissue using C14orf2 Polyclonal Antibody at dilution of 1:60(×200)