C4BPB Polyclonal Antibody
| 规格： | / 20μL / 60μL / 120μL / 200μL |
| 价格： | / ￥420 / ￥1010 / ￥1640 / ￥2365 |
货号：E-AB-52505
宿主: Rabbit
反应性: H
应用: IHC
Overview
| Synonyms | C4b binding protein beta chain,C4b-binding protein beta chain,C4BP,C4BPB,C4BPB,Complement component 4 binding protein beta,Complement component 4 binding protein beta chain,Complement component 4-binding protein beta,OTTHUMP00000034288,OTTHUMP00000034289,OTTHUMP00000034375,OTTHUMP0000003474,Proline rich protein,PRP,C4BPB抗体 |
| Swissprot | P20851 |
| Source | Rabbit |
| Reactivity | Human |
| Immunogen | Fusion protein of human C4BPB |
| Application | IHC(Detection kit: E-IR-R213) |
| Recommended dilution | IHC,,1:30-1:150 |
| Concentration | 0.7mg/mL |
| Clonality | Polyclonal |
Properties
| Cellular localization | Secreted. |
| Isotype | IgG |
| Purification | Affinity purification |
| Conjugation | Unconjugated |
| Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage buffer | PBS with 0.05% NaN3 and 40% Glycerol,pH7.4 |
| Background | This gene encodes a member of a superfamily of proteins composed predominantly of tandemly arrayed short consensus repeats of approximately 60 amino acids.A single, unique beta-chain encoded by this gene assembles with seven identical alpha-chains into the predominant isoform of C4b-binding protein, a multimeric protein that controls activation of the complement cascade through the classical pathway.C4b-binding protein has a regulatory role in the coagulation system also, mediated through the beta-chain binding of protein S, a vitamin K-dependent protein that serves as a cofactor of activated protein C.The genes encoding both alpha and beta chains are located adjacent to each other on human chromosome 1 in the regulator of complement activation gene cluster.Alternative splicing gives rise to multiple transcript variants. |
