C5AR1 Polyclonal Antibody
| 规格： | / 20μL / 60μL / 120μL / 200μL |
| 价格： | / ￥420 / ￥1010 / ￥1640 / ￥2365 |
货号：E-AB-18573
宿主: Rabbit
反应性: H
应用: IHC
Overview
| Synonyms | ANAPHYLATOXIN RECEPTOR,C5a anaphylatoxin chemotactic receptor,C5a anaphylatoxin receptor,C5A,C5a ligand,C5a-R,C5aR,C5AR,c5ar1,C5R1,CD88,CD88 antigen,Complement component 5 receptor 1,Complement component 5 receptor 2,Complement component 5a receptor 1,C5AR1抗体 |
| Swissprot | P21730 |
| Source | Rabbit |
| Reactivity | Human |
| Immunogen | Fusion protein of human C5AR1 |
| Application | IHC(Detection kit: E-IR-R213) |
| Recommended dilution | IHC,,1:40-1:200 |
| Concentration | 0.7mg/mL |
| Clonality | Polyclonal |
Properties
| Cellular localization | Cell membrane. |
| Isotype | IgG |
| Purification | Affinity purification |
| Conjugation | Unconjugated |
| Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage buffer | PBS with 0.05% NaN3 and 40% Glycerol,pH7.4 |
| Background | Receptor for the chemotactic and inflammatory peptide anaphylatoxin C5a (PubMed:1847994, PubMed:8182049, PubMed:7622471, PubMed:9553099, PubMed:10636859, PubMed:15153520). The ligand interacts with at least two sites on the receptor: a high-affinity site on the extracellular N-terminus, and a second site in the transmembrane region which activates downstream signaling events (PubMed:8182049, PubMed:7622471, PubMed:9553099). Receptor activation stimulates chemotaxis, granule enzyme release, intracellular calcium release and superoxide anion production (PubMed:10636859, PubMed:15153520). |
