c-Fos Monoclonal Antibody
| 规格： | / 20μL / 60μL / 120μL |
| 价格： | / ￥580 / ￥1420 / ￥2310 |
货号：E-AB-22158
宿主: Mouse
反应性: H,M,R
应用: WB,IHC-p
Overview
| Synonyms | Activator protein 1,AP 1,C FOS,Cellular oncogene c fos,Cellular oncogene fos,FBJ murine osteosarcoma viral (v fos) oncogene homolog (oncogene FOS),FBJ murine osteosarcoma viral oncogene homolog,FBJ murine osteosarcoma viral v fos oncogene homolog,FBJ Osteosarcoma Virus,FOS,FOS protein,FOS,G0 G1 switch regulatory protein 7,G0/G1 switch regulatory protein 7,G0S7,Oncogene FOS,p55,proto oncogene c Fos,Proto oncogene protein c fos,Proto-oncogene c-Fos,v fos FBJ murine osteosarcoma viral oncogene homolog,c-Fos抗体 |
| Swissprot | P01100 |
| Source | Mouse |
| Reactivity | Human,Mouse,Rat |
| Immunogen | Recombinant Protein |
| Application | WB(Detection kit: E-IR-R304),IHC-p(Detection kit: E-IR-R213) |
| Recommended dilution | WB,,1:500-1:2000;IHC,,1:100-1:300; |
| Concentration | 1mg/mL |
| Clonality | Monoclonal |
Properties
| Cellular localization | Nucleus. |
| Isotype | IgG |
| Purification | Protein A purification |
| Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage buffer | PBS with 0.02% sodium azide and 50% glycerol pH 7.4. |
| Background | Nuclear phosphoprotein which forms a tight but non-covalently linked complex with the JUN/AP-1 transcription factor. In the heterodimer, FOS and JUN/AP-1 basic regions each seems to interact with symmetrical DNA half sites. On TGF-beta activation, forms a multimeric SMAD3/SMAD4/JUN/FOS complex at the AP1/SMAD-binding site to regulate TGF-beta-mediated signaling. Has a critical function in regulating the Has a critical function in regulating the development of cells destined to form and maintain the skeleton. It is thought to have an important role in signal transduction, cell proliferation and differentiation. |
