c-Kit Polyclonal Antibody
| 规格： | / 60μL / 120μL / 200μL |
| 价格： | / ￥1380 / ￥2220 / ￥3300 |
货号：E-AB-70350
宿主: Rabbit
反应性: H,R
应用: IHC
Overview
| Synonyms | C Kit,c-Kit,c-Kit Ligand,CD117,Kit,Kit Ligand,KIT oncogene,KIT proto oncogene receptor tyrosine kinase,KIT,Mast cell growth factor receptor,Mast/stem cell growth factor receptor Kit,MGF,p145 c-kit,PBT,Piebald trait protein,Proto oncogene c Kit,Proto oncogene tyrosine protein kinase Kit,Proto-oncogene c-Kit,SCF Receptor,SCFR,soluble KIT variant 1,Steel Factor Receptor,Stem cell factor receptor,tyrosine protein kinase Kit,Tyrosine-protein kinase Kit,v kit Hardy Zuckerman 4 feline sarcoma viral oncogene homolog,v kit Hardy Zuckerman 4 feline sarcoma viral oncogene like protein,v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog,c-Kit抗体 |
| Swissprot | P10721,P05532 |
| Source | Rabbit |
| Reactivity | Human,Mouse,Rat |
| Immunogen | KLH conjugated Synthetic peptide corresponding to Mouse c-Kit |
| Application | IHC(Detection kit: E-IR-R213) |
| Recommended dilution | IHC,,1:200-1:1000 |
| Concentration | 400 μg/mL |
| Clonality | Polyclonal |
Properties
| Cellular localization | Cell membrane, Cytoplasm, Membrane |
| Tissue specificity | Isoform 1 and isoform 2 are detected in spermatogonia and Leydig cells. Isoform 3 is detected in round spermatids, elongating spermatids and spermatozoa (at protein level). Widely expressed. Detected in the hematopoietic system, the gastrointestinal system, in melanocytes and in germ cells.Highest expression level in epithelium of mammary gland. |
| Isotype | IgG |
| Purification | Affinity purification |
| Conjugation | Unconjugated |
| Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
| Storage buffer | PBS with 0.02% sodium azide,100 μg/ml BSA and 50% glycerol. |
| Background | This gene encodes the human homolog of the proto-oncogene c-kit. C-kit was first identified as the cellular homolog of the feline sarcoma viral oncogene v-kit. This protein is a type 3 transmembrane receptor for MGF (mast cell growth factor, also known as stem cell factor). Mutations in this gene are associated with gastrointestinal stromal tumors, mast cell disease, acute myelogenous lukemia, and piebaldism. Multiple transcript variants encoding different isoforms have been found for this gene. |
Images
Immunohistochemistry analysis of paraffin-embedded human tonsil using c-Kit Polyclonal Antibody at dilution of 1:200.
Immunohistochemistry analysis of paraffin-embedded human liver using c-Kit Polyclonal Antibody at dilution of 1:200.
Immunohistochemistry analysis of paraffin-embedded rat colon using c-Kit Polyclonal Antibody at dilution of 1:200.
