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CA9 Polyclonal Antibody(Capture/Detector)

规格: / 25μg / 100μg
价格: / 询价 / 询价

货号:AN003040P

货期:咨询

宿主: Rabbit

反应性: H

应用: ELISA Capture/Detector

  • 详情
  • Overview

    Synonyms CA9;CAIX;MN;CA-IX;Carbonate dehydratase IX;Carbonic Anhydrase IX;Carbonic Dehydratase;P54/58N;RCC;RCC-Associated Protein G250;G250;CAH9;Carbonic anhydrase 9;Membrane antigen MN;pMW1;RCC associated protein G250;RCC-associated antigen G250;Renal cell carcinoma-associated antigen G250
    Swissprot Q16790
    Source Rabbit
    Reactivity Human
    Immunogen Recombinant Human CA9 Protein expressed by Mammalian
    Application ELISA Capture/Detector
    Recommended dilution ELISA Capture,,2-8 μg/mL;ELISA Detector,,0.1-0.4 μg/mL
    Concentration 1mg/mL
    Clonality Polyclonal

    Properties

    Isotype IgG
    Purification Antigen Affinity Purification
    Conjugation Unconjugated
    Storage instructions Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles. This preparation contains no preservatives, thus it should be handled under aseptic conditions.
    Storage buffer Sterile PBS ,pH 7.4
    Background Carbonic anhydrases (CAs) are a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. They participate in a variety of biological processes, including respiration, calcification, acid-base balance, bone resorption, and the formation of aqueous humor, cerebrospinal fluid, saliva, and gastric acid. They show extensive diversity in tissue distribution and in their subcellular localization. CA IX is a transmembrane protein and is one of only two tumor-associated carbonic anhydrase isoenzymes known. It is expressed in all clear-cell renal cell carcinoma, but is not detected in normal kidney or most other normal tissues. It may be involved in cell proliferation and transformation. This gene was mapped to 17q21.2 by fluorescence in situ hybridization, however, radiation hybrid mapping localized it to 9p13-p12.
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