CA9 Polyclonal Antibody(Capture/Detector)
规格: | / 25μg / 100μg |
价格: | / 询价 / 询价 |
货号:AN003040P
货期:咨询
宿主: Rabbit
反应性: H
应用: ELISA Capture/Detector
Overview
Synonyms | CA9;CAIX;MN;CA-IX;Carbonate dehydratase IX;Carbonic Anhydrase IX;Carbonic Dehydratase;P54/58N;RCC;RCC-Associated Protein G250;G250;CAH9;Carbonic anhydrase 9;Membrane antigen MN;pMW1;RCC associated protein G250;RCC-associated antigen G250;Renal cell carcinoma-associated antigen G250 |
Swissprot | Q16790 |
Source | Rabbit |
Reactivity | Human |
Immunogen | Recombinant Human CA9 Protein expressed by Mammalian |
Application | ELISA Capture/Detector |
Recommended dilution | ELISA Capture,,2-8 μg/mL;ELISA Detector,,0.1-0.4 μg/mL |
Concentration | 1mg/mL |
Clonality | Polyclonal |
Properties
Isotype | IgG |
Purification | Antigen Affinity Purification |
Conjugation | Unconjugated |
Storage instructions | Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles. This preparation contains no preservatives, thus it should be handled under aseptic conditions. |
Storage buffer | Sterile PBS ,pH 7.4 |
Background | Carbonic anhydrases (CAs) are a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. They participate in a variety of biological processes, including respiration, calcification, acid-base balance, bone resorption, and the formation of aqueous humor, cerebrospinal fluid, saliva, and gastric acid. They show extensive diversity in tissue distribution and in their subcellular localization. CA IX is a transmembrane protein and is one of only two tumor-associated carbonic anhydrase isoenzymes known. It is expressed in all clear-cell renal cell carcinoma, but is not detected in normal kidney or most other normal tissues. It may be involved in cell proliferation and transformation. This gene was mapped to 17q21.2 by fluorescence in situ hybridization, however, radiation hybrid mapping localized it to 9p13-p12. |