CABIN1 Polyclonal Antibody
规格: | / 20μL / 60μL / 120μL / 200μL |
价格: | / ¥420 / ¥1010 / ¥1640 / ¥2365 |
货号:E-AB-17760
宿主: Rabbit
反应性: H,R
应用: IHC
Overview
Synonyms | A330070M20Rik,Cabin 1,CABIN,Cabin1,CAIN,Calcineurin binding protein cabin 1,Calcineurin inhibitor,Calcineurin-binding protein cabin-1,KIAA0330,PPP3IN,CABIN1抗体 |
Swissprot | Q9Y6J0 |
Source | Rabbit |
Reactivity | Human,Rat |
Immunogen | Synthetic peptide of human CABIN1 |
Application | IHC(Detection kit: E-IR-R213) |
Recommended dilution | IHC,,1:40-1:200 |
Concentration | 0.7mg/mL |
Clonality | Polyclonal |
Properties
Cellular localization | Nucleus. |
Isotype | IgG |
Purification | Affinity purification |
Conjugation | Unconjugated |
Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
Storage buffer | PBS with 0.05% NaN3 and 40% Glycerol,pH7.4 |
Background | Calcineurin plays an important role in the T-cell receptor-mediated signal transduction pathway. The protein encoded by this gene binds specifically to the activated form of calcineurin and inhibits calcineurin-mediated signal transduction. The encoded protein is found in the nucleus and contains a leucine zipper domain as well as several PEST motifs, sequences which confer targeted degradation to those proteins which contain them. Alternative splicing results in multiple transcript variants encoding two different isoforms. |