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CABIN1 Polyclonal Antibody

规格: / 20μL / 60μL / 120μL / 200μL
价格: / ¥420 / ¥1010 / ¥1640 / ¥2365

货号:E-AB-17760

宿主: Rabbit

反应性: H,R

应用: IHC

  • 详情
  • Overview

    Synonyms A330070M20Rik,Cabin 1,CABIN,Cabin1,CAIN,Calcineurin binding protein cabin 1,Calcineurin inhibitor,Calcineurin-binding protein cabin-1,KIAA0330,PPP3IN,CABIN1抗体
    Swissprot Q9Y6J0
    Source Rabbit
    Reactivity Human,Rat
    Immunogen Synthetic peptide of human CABIN1
    Application IHC(Detection kit: E-IR-R213)
    Recommended dilution IHC,,1:40-1:200
    Concentration 0.7mg/mL
    Clonality Polyclonal

    Properties

    Cellular localization Nucleus.
    Isotype IgG
    Purification Affinity purification
    Conjugation Unconjugated
    Storage instructions Store at -20℃. Avoid freeze / thaw cycles.
    Storage buffer PBS with 0.05% NaN3 and 40% Glycerol,pH7.4
    Background Calcineurin plays an important role in the T-cell receptor-mediated signal transduction pathway. The protein encoded by this gene binds specifically to the activated form of calcineurin and inhibits calcineurin-mediated signal transduction. The encoded protein is found in the nucleus and contains a leucine zipper domain as well as several PEST motifs, sequences which confer targeted degradation to those proteins which contain them. Alternative splicing results in multiple transcript variants encoding two different isoforms.
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