CALB1 Polyclonal Antibody
规格: | / 20μL / 60μL / 120μL / 200μL |
价格: | / ¥420 / ¥1010 / ¥1640 / ¥2365 |
货号:E-AB-11020
宿主: Rabbit
反应性: H,M,R
应用: WB,IHC
Overview
Synonyms | avian-type,CAB27,CALB 1,CALB,CALB1,CALB1,Calbindin 1 28kDa,Calbindin,Calbindin D28,D 28K,D-28K,D28K,OTTHUMP00000166027,OTTHUMP00000225441,RTVL H protein,Vitamin D dependent calcium binding protein,Vitamin D dependent calcium binding protein avian type,Vitamin D-dependent calcium-binding protein,CALB1抗体 |
Swissprot | P05937 |
Source | Rabbit |
Reactivity | Human,Mouse,Rat |
Immunogen | Recombinant protein of human CALB1 |
Application | WB(Detection kit: E-IR-R304),IHC(Detection kit: E-IR-R213) |
Recommended dilution | WB,,1:500-1:2000;IHC,,1:50-1:200; |
Concentration | 0.4 mg/mL |
Clonality | Polyclonal |
Properties
Cellular localization | Cytosol,Extracellular region or secreted,extracellular exosome,Nucleus,Other locations:axon,dendrite,dendritic spine,neuronal cell body,synapse,terminal bouton |
Isotype | IgG |
Purification | Affinity purification |
Conjugation | Unconjugated |
Storage instructions | Store at -20℃. Avoid freeze / thaw cycles. |
Storage buffer | PBS with 0.05% sodium azide, 50% glycerol, PH7.3 |
Background | Calbindin is a calcium-binding protein belonging to the troponin C superfamily. It was originally described as a 27-kD protein induced by vitamin D in the duodenum of the chick. In the brain, its synthesis is independent of vitamin-D-derived hormones. Calbindin contains 4 active calcium-binding domains, and 2 modified domains that presumably have lost their calcium-binding capacity. The neurons in brains of patients with Huntington disease are calbindin-depleted. |